Evidence map›Paper›PMID 35344045›Full record

ArticleJAMA network open2022

Racial Disparities in COVID-19 Outcomes Among Black and White Patients With Cancer.

Julie Fu, Sonya A Reid, Benjamin French, Cassandra Hennessy, Clara Hwang, Na Tosha Gatson, Narjust Duma, Sanjay Mishra, Ryan Nguyen, Jessica E Hawley and 19 more

Erratum issuedAbstract read
In one paragraph

Article in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Julie FuDepartment of Internal Medicine, Hematology-Oncology, Tufts Medical Center Cancer Center, Stoneham, Massachusetts.
Sonya A ReidDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University, Nashville, Tennessee.
Benjamin FrenchDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee.
Cassandra HennessyDepartment of Biostatistics, Vanderbilt University, Nashville, Tennessee.
Clara HwangDepartment of Internal Medicine, Division of Hematology-Oncology, Henry Ford Cancer Institute, Detroit, Michigan.
Na Tosha GatsonGeisinger Health System, Danville, Danville, Pennsylvania.
Narjust DumaDivision of Medical Oncology, Department of Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts.
Sanjay MishraVanderbilt-Ingram Cancer Center at Vanderbilt University Medical Center, Nashville, Tennessee.
Ryan NguyenDepartment of Hematology and Oncology, University of Illinois, Chicago.
Jessica E HawleyHerbert Irving Comprehensive Cancer Center at Columbia University, New York, New York.
Sunny R K SinghDepartment of Internal Medicine, Division of Hematology-Oncology, Henry Ford Cancer Institute, Detroit, Michigan.
David D ChismThompson Cancer Survival Center, Knoxville, Tennessee.
Neeta K VenepalliDivision of Oncology, Department of Medicine, University of North Carolina, Chapel Hill.
Jeremy L WarnerDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University, Nashville, Tennessee.
Toni K ChoueiriDivision of Medical Oncology, Department of Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts.
Andrew L SchmidtDivision of Medical Oncology, Department of Medicine, Dana-Farber Cancer Institute, Boston, Massachusetts.
Leslie A FecherRogel Cancer Center, University of Michigan, Ann Arbor.
Jennifer E GirardRogel Cancer Center, University of Michigan, Ann Arbor.
Mehmet A BilenDepartment of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Deepak RavindranathanDepartment of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Sharad GoyalDepartment of Radiation Oncology, George Washington University, Washington, DC.
Trisha M Wise-DraperDepartment of Internal Medicine, Division of Hematology-Oncology, University of Cincinnati Cancer Center, Cincinnati, Ohio.
Cathleen ParkDepartment of Hematology-Oncology, University of California, Davis.
Corrie A PainterCount Me In, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
Sheila M McGlownPatient advocate.
Gilberto de Lima LopesSylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, Miami, Florida.
Oscar K SerranoDepartment of Surgery, Hartford HealthCare Cancer Institute, Hartford, Connecticut.
Dimpy P ShahPopulation Health Sciences, Mays Cancer Center at University of Texas Health San Antonio MD Anderson, San Antonio.
COVID-19 and Cancer Consortium (CCC19)

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCATS NIH HHS UL1 TR000445NCI NIH HHS K12 CA090625NCI NIH HHS P30 CA054174NCI NIH HHS P30 CA068485NCI NIH HHS P30 CA123456NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

Importance: Non-Hispanic Black individuals experience a higher burden of COVID-19 than the general population; hence, there is an urgent need to characterize the unique clinical course and outcomes of COVID-19 in Black patients with cancer. Objective: To investigate racial disparities in severity of COVID-19 presentation, clinical complications, and outcomes between Black patients and non-Hispanic White patients with cancer and COVID-19. Design, Setting, and Participants: This retrospective cohort study used data from the COVID-19 and Cancer Consortium registry from March 17, 2020, to November 18, 2020, to examine the clinical characteristics and outcomes of COVID-19 in Black patients with cancer. Data analysis was performed from December 2020 to February 2021. Exposures: Black and White race recorded in patient's electronic health record. Main Outcomes and Measures: An a priori 5-level ordinal scale including hospitalization intensive care unit admission, mechanical ventilation, and all-cause death. Results: Among 3506 included patients (1768 women [50%]; median [IQR] age, 67 [58-77] years), 1068 (30%) were Black and 2438 (70%) were White. Black patients had higher rates of preexisting comorbidities compared with White patients, including obesity (480 Black patients [45%] vs 925 White patients [38%]), diabetes (411 Black patients [38%] vs 574 White patients [24%]), and kidney disease (248 Black patients [23%] vs 392 White patients [16%]). Despite the similar distribution of cancer type, cancer status, and anticancer therapy at the time of COVID-19 diagnosis, Black patients presented with worse illness and had significantly worse COVID-19 severity (unweighted odds ratio, 1.34 [95% CI, 1.15-1.58]; weighted odds ratio, 1.21 [95% CI, 1.11-1.33]). Conclusions and Relevance: These findings suggest that Black patients with cancer experience worse COVID-19 outcomes compared with White patients. Understanding and addressing racial inequities within the causal framework of structural racism is essential to reduce the disproportionate burden of diseases, such as COVID-19 and cancer, in Black patients.

Indexed as

COVID-19NeoplasmsAgedBlack PeopleCOVID-19 TestingFemaleHumansRetrospective Studies

Identifiers

PMID35344045
PMCPMC8961318

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.