Evidence map›Paper›PMID 35343781›Full record

ArticleAntimicrobial agents and chemotherapy2022

Deciphering the Mrr1/Mdr1 Pathway in Azole Resistance of Candida auris.

Jizhou Li, Alix T Coste, Daniel Bachmann, Dominique Sanglard, Frederic Lamoth

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Deciphering the multidrug resistance paradigm inAntimicrobial agents and chemotherapy · 2026
    Review
  6. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  7. Article
  8. Relative contributions of the ERG11Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2026
    Article
  9. Article
  10. Genomic Insights intoJournal of fungi (Basel, Switzerland) · 2026
    Article
  11. bioRxiv : the preprint server for biology · 2026
    Article
  12. ER stress selects forFrontiers in microbiology · 2026
    Article
  13. Resistance gene mutations and phylogenetic relationships inFrontiers in cellular and infection microbiology · 2026
    Article
  14. Article
  15. Article
  16. First Report ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  17. Mutations inAntimicrobial agents and chemotherapy · 2025
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jizhou LiInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Alix T CosteInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Daniel BachmannInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Dominique SanglardInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-5244-4178
Frederic LamothInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-1023-5597
University of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida auris is an emerging yeast pathogen with a remarkable ability to develop antifungal resistance, in particular to fluconazole and other azoles. Azole resistance in C. auris was shown to result from different mechanisms, such as mutations in the target gene

Indexed as

AzolesFluconazoleAntifungal AgentsCandida albicansCandida aurisDrug Resistance, FungalFungal ProteinsMicrobial Sensitivity TestsTranscription FactorsAntifungal AgentsAzolesFluconazoleFungal ProteinsTranscription Factorsdrug transportersefflux pumpsfluconazoletranscription factorsvoriconazole

Identifiers

PMID35343781
PMCPMC9017311
OpenAlexW4220984632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.