Evidence map›Paper›PMID 35343774›Full record

ArticleJournal of bacteriology2022

Enteroinvasive Escherichia coli O96:H19 is an Emergent Biofilm-Forming Pathogen.

Junaid Iqbal, Niharika Malviya, Jennifer A Gaddy, Chengxian Zhang, Andrew J Seier, Kathryn P Haley, Ryan S Doster, Ana E Farfán-García, Oscar G Gómez-Duarte

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. First recorded food-borne outbreak of gastroenteritis caused by enteroinvasive Escherichia coli serotype O8:H19 in Thailand.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Junaid IqbalDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Niharika MalviyaDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Jennifer A GaddyDivision of Infectious Diseases, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Chengxian ZhangDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Andrew J SeierInternational Enteric Vaccine Research Program, Division of Pediatric Infectious Diseases, State University of New York at Buffalo, Buffalo, New York, USA.
Kathryn P HaleyDivision of Infectious Diseases, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.
Ryan S DosterDivision of Infectious Diseases, Vanderbilt University School of Medicinegrid.471397.f, Nashville, Tennessee, USA.ORCID 0000-0001-7376-1298
Ana E Farfán-GarcíaUniversidad de Santandergrid.441435.3, Facultad de Ciencias Médicas y de la Salud, Instituto de Investigación Masira, Bucaramanga, Colombia.
Oscar G Gómez-DuarteInternational Enteric Vaccine Research Program, Division of Pediatric Infectious Diseases, State University of New York at Buffalo, Buffalo, New York, USA.ORCID 0000-0001-5628-5760
Vanderbilt University · USUniversity at Buffalo, State University of New York · USAga Khan University · PKUnited States Department of Veterans Affairs · USUniversidad De Santander · CO

Funding

Determining the contribution of zinc deficiency to perinatal Group B Streptococcus infectionsR01HD090061 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M, GADDY, JENNIFER A · 2017 to 2021
$2.5M
The Role of macrophages in chorioamnionitis and group B streptococcal infectionsR01AI134036 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M · 2017 to 2021
$2.4M
Studies on Emergent Diarrheagenic E. coli PathogensR01AI095346 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOMEZ, OSCAR G · 2013 to 2017
$1.9M
Defining the impact of zinc on Streptococcus agalactiae biofilm and colonizationK08AI151100 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DOSTER, RYAN S · 2020 to 2024
$927k
Regulation of Helicobacter pylori pili encoded by the cag pathogenicity islandIK2BX001701 · VA · VETERANS HEALTH ADMINISTRATION · PI GADDY, JENNIFER A · 2013 to 2017
–
BLRD VA IK2 BX001701NIAID NIH HHS K08 AI151100NIAID NIH HHS R01 AI095346NIAID NIH HHS R01 AI134036NICHD NIH HHS R01 HD090061
6 · The paper itself

Abstract

Enteroinvasive Escherichia coli (EIEC) is a diarrheagenic E. coli pathotype carrying a virulence plasmid that encodes a type III secretion system (TTSS) directly implicated in bacterial cell invasion. Since 2012, EIEC serotype O96:H19 has been recognized in Europe, Colombia, and most recently Uruguay. In addition to the invasion phenotype, the strains isolated from Colombian children with moderate-to-severe gastroenteritis had a strong biofilm formation phenotype, and as a result, they are referred to as biofilm-forming enteroinvasive E. coli (BF-EIEC). The objective of this study was to characterize the biofilm formation phenotype of the BF-EIEC O96:H19 strain 52.1 isolated from a child with moderate-to-severe gastroenteritis in Colombia. Random mutagenesis using Tn

Indexed as

Escherichia coli InfectionsGastroenteritisShigellaBiofilmsChild, PreschoolEscherichia coliHumansPhylogenyType III Secretion SystemsType III Secretion Systemsbiofilm formationchildrendiarrheaemerging pathogenenteroinvasiveenteroinvasive Escherichia coliEscherichia coli

Identifiers

PMID35343774
PMCPMC9017384
OpenAlexW4220656058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.