Evidence map›Paper›PMID 35343611›Full record

ArticleThe Journal of dermatology2022

Patient and physician perspectives on alopecia areata: A real-world assessment of severity and burden in Japan.

Emily Edson-Heredia, Toshihiko Aranishi, Yoshitaka Isaka, Peter Anderson, Simran Marwaha, James Piercy

Open access · hybridAbstract read
In one paragraph

Article in The Journal of dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  15. Eyebrow and Eyelash Alopecia: A Clinical Review.American journal of clinical dermatology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Emily Edson-HerediaEli Lilly & Company, Indianapolis, Indiana, USA.
Toshihiko AranishiEli Lilly Japan K.K., Kobe, Japan.
Yoshitaka IsakaEli Lilly Japan K.K., Kobe, Japan.
Peter AndersonAdelphi Real World, Bollington, UK.
Simran MarwahaAdelphi Real World, Bollington, UK.
James PiercyAdelphi Real World, Bollington, UK.
Adelphi Group (United Kingdom) · GBEli Lilly (Japan) · JPEli Lilly (United States) · US

Funding

Eli Lilly and Company
6 · The paper itself

Abstract

The criteria used by physicians to assess alopecia areata severity and its associated burden from the patients' point of view are not well understood. We aimed to understand physician-assessed determinants of disease severity, factors associated with severity, patient-physician concordance, and patient-reported burden by severity. Data were drawn from the Adelphi Alopecia Areata Disease Specific Programme™, a point-in-time survey of dermatologists and their alopecia areata patients in real-world practice in Japan conducted between January and March 2021. Patients were categorized into three groups by current disease severity according to physician subjective assessment: mild, moderate, or severe. Demographics, clinical characteristics, and outcomes were described within and compared between the three patient groups. Our study of 97 dermatologists and 587 patients found overall scalp hair loss was the most important factor considered by physicians in determining disease severity. More severe disease was associated with loss of eyebrow hair, eyelashes, and hair loss from other body areas. Agreement on disease severity between physicians and patients was moderate. From the patient perspective, greater severity of alopecia areata was associated with greater anxiety and depression, with lower work productivity and worse quality of life. Our study provides insights into which factors physicians use to determine alopecia areata severity, how physician and patient severity assessments compare, and the burden of alopecia areata on patients.

Indexed as

Alopecia AreataPhysiciansAlopeciaHumansJapanQuality of Lifealopecia areatadermatologyoutcomes researchquality of lifeseverity of illness

Identifiers

PMID35343611
PMCPMC9310764
OpenAlexW4220659363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.