Evidence map›Paper›PMID 35343593›Full record

ArticleEpilepsia2022

Using magnetic resonance fingerprinting to characterize periventricular nodular heterotopias in pharmacoresistant epilepsy.

Joon Yul Choi, Balu Krishnan, Siyuan Hu, David Martinez, Yinging Tang, Xiaofeng Wang, Ken Sakaie, Stephen Jones, Hiroatsu Murakami, Ingmar Blümcke and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Anti-seizure effects of WS-3, a TRPM8 agonist, on focal onset seizure mouse model via reduction of extracellular glutamate levels.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Joon Yul ChoiCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.
Balu KrishnanCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.ORCID 0000-0002-1897-3359
Siyuan HuBiomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
David MartinezCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.
Yinging TangCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.ORCID 0000-0001-5813-0308
Xiaofeng WangQuantitative Health Science, Cleveland Clinic, Cleveland, Ohio, USA.
Ken SakaieImaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Stephen JonesImaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Hiroatsu MurakamiCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.
Ingmar BlümckeCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.ORCID 0000-0001-8676-0788
Imad NajmCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.ORCID 0000-0001-5192-2089
Dan MaBiomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Zhong Irene WangCharles Shor Epilepsy Center, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA.ORCID 0000-0002-3829-5217
Cleveland Clinic · USCase Western Reserve University · US

Funding

MR Fingerprinting for EpilepsyR01NS109439 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI Dan Ma, Zhong Irene Wang · 2019 to 2026
$4.2M
A Framework to Design 3D Quantitative Magnetic Resonance Fingerprinting (MRF) Scans and Reduce Patient AnxietyR21EB026764 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI MA, DAN · 2018 to 2020
$641k
NIBIB NIH HHS R21 EB026764NINDS NIH HHS R01 NS109439
6 · The paper itself

Abstract

objectiveWe aimed to use a novel magnetic resonance fingerprinting (MRF) technique to examine in vivo tissue property characteristics of periventricular nodular heterotopia (PVNH). These characteristics were further correlated with stereotactic-electroencephalographic (SEEG) ictal onset findings.

methodsWe included five patients with PVNH who had SEEG-guided surgery and at least 1 year of seizure freedom or substantial seizure reduction. High-resolution MRF scans were acquired at 3 T, generating three-dimensional quantitative T

resultsIndividual-level analysis showed T SIGNIFICANCE: Quantitative MRF measures, especially T

Indexed as

EpilepsyPeriventricular Nodular HeterotopiaElectroencephalographyHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopySeizuresmagnetic resonance imagingMR fingerprintingperiventricular nodular heterotopiastereotactic electroencephalographyT1 relaxation time

Identifiers

PMID35343593
PMCPMC9081261
OpenAlexW4221071154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.