Evidence map›Paper›PMID 35343438›Full record

ArticleeLife2022

Impact of a human gut microbe on

Kelsey Barrasso, Denise Chac, Meti D Debela, Catherine Geigel, Anjali Steenhaut, Abigail Rivera Seda, Chelsea N Dunmire, Jason B Harris, Regina C Larocque, Firas S Midani and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Virulence · 2026
    Article
  2. Actuation of CRP activating region 3 by formylation modulates theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. A biofilm-derived peptide as an underwater adhesive.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
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  7. Article
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  11. Article
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  13. Antimicrobial and antibiofilm activities of formylchromones againstFrontiers in cellular and infection microbiology · 2023
    Article
  14. Article
  15. Intestinal colonization againstAIMS microbiology · 2023
    Review
  16. Gut dysbiosis in autoimmune diseases: Association with mortality.Frontiers in cellular and infection microbiology · 2023
    Review
  17. Social evolution of shared biofilm matrix components.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Kelsey BarrassoDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, United States.
Denise ChacDepartment of Medicine, University of Washington, Seattle, United States.
Meti D DebelaDivision of Infectious Diseases, Massachusetts General Hospital, Boston, United States.
Catherine GeigelDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.
Anjali SteenhautDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, United States.
Abigail Rivera SedaDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, United States.
Chelsea N DunmireDepartment of Medicine, University of Washington, Seattle, United States.
Jason B HarrisDivision of Infectious Diseases, Massachusetts General Hospital, Boston, United States.
Regina C LarocqueDivision of Infectious Diseases, Massachusetts General Hospital, Boston, United States.
Firas S MidaniDepartment of Molecular Virology and Microbiology at Baylor College of Medicine, Houston, United States.ORCID 0000-0002-2473-7758
Firdausi QadriInternational Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh.
Jing YanDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, United States.
Ana A WeilDepartment of Medicine, University of Washington, Seattle, United States.ORCID 0000-0002-6170-4306
Wai-Leung NgDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, United States.ORCID 0000-0002-8966-6604
Tufts University · USUniversity of Washington · USMassachusetts General Hospital · USYale University · USHarvard University · USInternational Centre for Diarrhoeal Disease Research · BD

Funding

Research Training in Pediatrics GastroenterolgyT32DK007664 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI DOUGLAS G BURRIN · 1991 to 2026
$8.4M
Tufts Post-Baccalaureate Research Education ProgramR25GM066567 · NIGMS · TUFTS UNIVERSITY BOSTON · PI RIOS, MARIBEL · 2002 to 2024
$5.7M
SIGNALING MECHANISMS IN VIBRIO CHOLERAE PARALLEL QUORUM SENSING PATHWAYSR01AI121337 · NIAID · TUFTS UNIVERSITY BOSTON · PI NG, WAI-LEUNG · 2016 to 2025
$4.5M
Antibody mediated protective immunity against choleraR01AI137164 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C, HARRIS, JASON B · 2018 to 2022
$3.9M
Tracking single-cell gene expression heterogeneity and its consequences in bacterial biofilmsDP2GM146253 · NIGMS · YALE UNIVERSITY · PI YAN, JING · 2021 to 2024
$2.5M
The gut microbiome and susceptibility to Vibrio choleraeK08AI123494 · NIAID · UNIVERSITY OF WASHINGTON · PI WEIL, ANA A · 2016 to 2020
$967k
NIAID NIH HHS K08 AI123494NIAID NIH HHS R01 AI121337NIAID NIH HHS R01 AI137164NIDDK NIH HHS T32 DK007664NIGMS NIH HHS DP2 GM146253NIGMS NIH HHS R25 GM066567
6 · The paper itself

Abstract

Recent studies indicate that the human intestinal microbiota could impact the outcome of infection by

Indexed as

CholeraGastrointestinal MicrobiomeVibrio choleraeAnimalsBiofilmsHumansMiceVirulencebiofilminfectious diseasemicrobiologymicrobiomeParacoccus aminovoranspathogenesisVibrio cholerae

Identifiers

PMID35343438
PMCPMC8993218
OpenAlexW4225933223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.