Evidence map›Paper›PMID 35343271›Full record

ArticleCell transplantation

Bone Marrow Mononuclear Cells Restore Normal Mitochondrial Ca

Clara Rodrigues-Ferreira, Jarlene Alécia Lopes, Priscila Fonseca Carneiro, Cristiane Dos Santos Lessa, Antonio Galina, Adalberto Vieyra

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clara Rodrigues-FerreiraCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Jarlene Alécia LopesCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Priscila Fonseca CarneiroCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Cristiane Dos Santos LessaLeopoldo de Meis Institute of Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Antonio GalinaLeopoldo de Meis Institute of Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Adalberto VieyraCarlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0002-8009-7273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury due to ischemia followed by reperfusion (IR) is a severe clinical condition with high death rates. IR affects the proximal tubule segments due to their predominantly oxidative metabolism and profoundly altered mitochondrial functions. We previously described the impact of IR on oxygen consumption, the generation of membrane potential (ΔΨ), and formation of reactive oxygen species, together with inflammatory and structural alterations. We also demonstrated the benefits of bone marrow mononuclear cells (BMMC) administration in these alterations. The objective of the present study has been to investigate the effect of IR and the influence of BMMC on the mechanisms of Ca

Indexed as

Bone MarrowMitochondrial MembranesCalciumHumansIschemiaMitochondriaPermeabilityReperfusionCalciumbone marrow mononuclear cellsmitochondrial Ca2+ handlingmitochondrial membrane potentialpermeability transition porerenal ischemia/reperfusion

Identifiers

PMID35343271
PMCPMC8958683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.