Evidence map›Paper›PMID 35343206›Full record

ArticleIndian journal of pharmacology

Update on omicron variant: What we know so far.

Gajendra Choudhary, Manisha Prajapat, J Kumaravel, Praisy K Prabha, Phulen Sarma, Vrishbhanu Handa, Harminder Kaur, Ajay Prakash Patel, Bikash Medhi

Abstract read
In one paragraph

Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gajendra ChoudharyDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manisha PrajapatDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J KumaravelDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Praisy K PrabhaDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Phulen SarmaDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vrishbhanu HandaDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Harminder KaurDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ajay Prakash PatelDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Bikash MedhiDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in South Africa in November 2021 has been declared as a Variant of Concern by the World Health Organization. This variant has been found to carry multifold mutations that have not been observed in any of the variants detected so far. The majority of these mutations are present in spike protein, contributing to its ability to escape the currently available neutralizing antibodies and vaccines, as well as increasing the chances of reinfection. This brief communication provides an insight into mutations detected in the omicron variant and their impact on currently available interventions against SARS-CoV-2 and the need for a booster dose. We also discuss the severity status of infection due to this variant. Additionally, we highlight the hypothesis supporting the association of high HIV prevalence and the appearance of the omicron variant of SARS-CoV-2 in immune-compromised individuals.

Indexed as

COVID-19Viral Envelope ProteinsAntibodies, ViralHumansSARS-CoV-2Antibodies, ViralViral Envelope ProteinsCOVID-19HIVmutationsomicronsevere acute respiratory syndrome coronavirus 2variant

Identifiers

PMID35343206
PMCPMC9012418

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.