ArticleClinical and translational medicine2022
The IL-21-TET2-AIM2-c-MAF pathway drives the T follicular helper cell response in lupus-like disease.
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Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
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Who cites it
26 citing papers in PubMed, 45 citations in OpenAlex.
- Epigenetic regulation of B cell tolerance and dysfunction in autoimmune disease.Nature reviews. Immunology · 2026Review
- Is clonal haematopoiesis the missing link between lupus and cardiovascular disease?Rheumatology (Oxford, England) · 2026Review
- AIM2 positively regulates B cell activation and function through the SNX9-PI3K-WASP axis.Cell death and differentiation · 2026Article
- Impact of Absent in Melanoma 2 (AIM2) on Antigen-Specific CD4+ T cell Activation and Homeostasis.bioRxiv : the preprint server for biology · 2025Article
- Inflammasomes and autophagy in cancer: unlocking targeted therapies.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Ten-Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy.MedComm · 2025Review
- Follicular helper T cells (Tfh): heterogeneity in spatial distribution and phenotypic characteristics.Frontiers in immunology · 2025Review
- Transcription factor c-Maf: a checkpoint that programs autoimmunity.Frontiers in immunology · 2025Review
- Mesenchymal Stem Cell-Derived Exosomes Inhibit Stim1-Orai1 Signaling and Calcium Overload-Induced Mitochondrial Damage of Follicular Helper T Cells in Lupus.Biomaterials research · 2025Article
- Eosinophils in Rheumatoid Arthritis: A Multifaceted Role in the Pathogenesis of the Disease.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2025Article
- Cross-talk between aging resilience pathways and autoimmunity onset.Frontiers in immunology · 2025Review
- Epigenetics-targeted drugs: current paradigms and future challenges.Signal transduction and targeted therapy · 2024Review
- Deciphering the interplay of HPV infection, MHC-II expression, and CXCL13Cancer immunology, immunotherapy : CII · 2024Article
- Cytokines in Follicular Helper T Cell Biology in Physiologic and Pathologic Conditions.Immune network · 2024Review
- The role of inflammasomes in human diseases and their potential as therapeutic targets.Signal transduction and targeted therapy · 2024Review
- The role of AIM2 in inflammation and tumors.Frontiers in immunology · 2024Review
- The Role of the AIM2 Gene in Obesity-Related Glucose and Lipid Metabolic Disorders: A Recent Update.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- The roles of AIM2 in neurodegenerative diseases: insights and therapeutic implications.Frontiers in immunology · 2024Review
- AIM2 promotes TiScience · 2023Article
- Review
Corrections and comments
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Authors and funding
18 authors at 2 institutions in 3 countries.
Haijing WuDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Yaxiong DengDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.ORCID 0000-0001-6433-3232
Di LongDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Ming YangDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Qianwen LiDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Yu FengDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Yongjian ChenDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Hong QiuDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Xin HuangDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Zhenghao HeDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Longyuan HuDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Heng YinDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Guangdi LiDepartment of Public Health, Central South University, Changsha, China.
Yunkai GuoDepartment of Otolaryngology Head and Neck Surgery, Second Xiangya Hospital, Central South University, Changsha, China.
Wenhan DuDepartment of Pathology and Center for Infection and Immunology, The University of Hong Kong, Chongqing International Institute for Immunology, Hong Kong, China.
Ming ZhaoDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Liwei LuDepartment of Pathology and Center for Infection and Immunology, The University of Hong Kong, Chongqing International Institute for Immunology, Hong Kong, China.
Qianjin LuDepartment of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Central South University · CNHong Kong Baptist University · HK
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves T follicular helper (T
Indexed as
DioxygenasesLupus Erythematosus, SystemicAnimalsDNA-Binding ProteinsHumansInterleukin-21InterleukinsMiceProto-Oncogene Proteins c-mafT Follicular Helper CellsAIM2 protein, humanAim2 protein, mouseDioxygenasesDNA-Binding ProteinsInterleukin-21InterleukinsMaf protein, mouseProto-Oncogene Proteins c-mafTET2 protein, humanTet2 protein, mouseAIM2systemic lupus erythematosus (SLE)T follicular helper cells (TFH)
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.