Evidence map›Paper›PMID 35342933›Full record

ArticleEuropean journal of clinical investigation2022

The prognostic role of interatrial block among COVID-19 patients hospitalized in medicine wards.

Vincenzo Russo, Stefano Albani, Alfredo Caturano, Sara Hana Weisz, Valentina Parisi, Maddalena Conte, Lorenzo Zaccaro, Antonello D'Andrea, Ahmed Al-Turky, Michal Marchel and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. The Impact of Antiretroviral Therapy on Electrocardiographic Parameters in Human Immundeficiency Virus-Positive Patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
    Article
  2. Article
  3. Article
  4. Interatrial block, atrial fibrillation, and thrombotic events in COVID-19.European journal of clinical investigation · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Vincenzo RussoDivision of Cardiology, Department of Translational Medical Sciences, Monaldi and Cotugno Hospital, University of Campania 'Luigi Vanvitelli', Naples, Italy.ORCID https://orcid.org/0000-0002-9227-0360
Stefano AlbaniCardiology Department, Aosta Valley Health Authority, Aosta, Italy.ORCID https://orcid.org/0000-0002-1407-6087
Alfredo CaturanoDepartment of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.ORCID https://orcid.org/0000-0001-7761-7533
Sara Hana WeiszDivision of Cardiology, Cotugno Hospital, Naples, Italy.
Valentina ParisiDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.
Maddalena ConteDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.
Lorenzo ZaccaroCardiology Department, Aosta Valley Health Authority, Aosta, Italy.
Antonello D'AndreaDivision of Cardiology, Umberto I Hospital, Nocera Inferiore, Italy.ORCID https://orcid.org/0000-0002-9698-9145
Ahmed Al-TurkyDivision of Cardiology, McGill University Health Centre, Montreal, Quebec, Canada.
Michal MarchelCardiology Unit, Monaldi Hospital, Naples, Italy.
Marco MaranoMaria Rosaria Hospital, Pompei, Italy.
Ferdinando Carlo SassoDepartment of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.ORCID https://orcid.org/0000-0002-9142-7848
Emilio AttenaCardiology Unit, Monaldi Hospital, Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITOspedale Monaldi · ITUniversity of Aosta Valley · ITUniversity of Naples Federico II · ITMcGill University Health Centre · CAOspedale D. Cotugno · ITPoliclinico Umberto I · ITSanta Maria Nuova Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSome abnormal electrocardiographic findings were independently associated with increased mortality in patients admitted for COVID-19; however, no studies have focussed on the prognosis impact of the interatrial block (IAB) in this clinical setting. The aim of our study was to assess the prevalence and clinical implications of IAB, both partial and advanced, in hospitalized COVID-19 patients. MATERIALS: We retrospectively evaluated 300 consecutive COVID-19 patients (63.22 ± 15.16 years; 70% males) admitted to eight Italian Hospitals from February 2020 to April 2020 who underwent twelve lead electrocardiographic recording at admission. The study population has been dichotomized into two groups according to the evidence of IAB at admission, both partial and advanced. The differences in terms of ARDS in need of intubation, in-hospital mortality and thromboembolic events (a composite of myocardial infarction, stroke and transient ischaemic attack) have been evaluated.

resultsThe presence of IAB was noticed in 64 patients (21%). In the adjusted logistic regression model, the partial interatrial block was found to be an independent predictor of ARDS in need of intubation (HR: 1.92; p: .04) and in-hospital mortality (HR: 2.65; p: .02); moreover, the advanced interatrial block was an independent predictor of thrombotic events (HR: 7.14; p < .001).

conclusionsAmong COVID-19 patients hospitalized in medical wards, the presence of interatrial block is more frequent than in the general population and it might be useful as an early predictor for increased risk of incident thrombotic events, ARDS in need of intubation and in-hospital mortality.

Indexed as

Atrial FibrillationCOVID-19Respiratory Distress SyndromeElectrocardiographyFemaleHospitalsHumansInteratrial BlockMalePrognosisRetrospective Studiesacute respiratory distress syndromeatrial fibrillationCOVID-19interatrial blockmortalitynovel coronavirusoutcomeSARS-CoV-2

Identifiers

PMID35342933
PMCPMC9111721
OpenAlexW4220772270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.