Evidence map›Paper›PMID 35342824›Full record

ArticleEPiC series in computing2019

A New Look at Codon Usage and Protein Expression.

Gabriel Wright, Anabel Rodriguez, Patricia L Clark, Scott Emrich

Open access · bronzeAbstract read
In one paragraph

Article in EPiC series in computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gabriel WrightDepartment of Computer Science, University of Notre Dame.
Anabel RodriguezDepartment of Chemistry & Biochemistry, University of Notre Dame.
Patricia L ClarkDepartment of Chemistry & Biochemistry, University of Notre Dame.
Scott EmrichDepartment of Electrical Engineering & Computer Science, University of Tennessee, Knoxville.
University of Notre Dame · US

Funding

Integrative computational framework for pattern mining in big -omics data: linking synonymous codon usage to protein biogenesisR01GM120733 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CLARK, PATRICIA LOUISE, EMRICH, SCOTT · 2016 to 2019
$1.1M
NIGMS NIH HHS R01 GM120733
6 · The paper itself

Abstract

%MinMax, a model of intra-gene translational elongation rate, relies on codon usage frequencies. Historically, %MinMax has used tables that measure codon usage bias for all genes in an organism, such as those found at HIVE-CUT. In this paper, we provide evidence that codon usage bias based on all genes is insufficient to accurately measure absolute translation rate. We show that alternative "High-

Identifiers

PMID35342824
PMCPMC8953497
OpenAlexW3009334801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.