ArticleEuropean stroke journal2021
Accuracy of CTA evaluations in daily clinical practice for large and medium vessel occlusion detection in suspected stroke patients.
Article in European stroke journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Time to Endovascular Treatment and Clinical Outcome in Acute Ischemic Stroke With M2-Segment Occlusion.Journal of the American Heart Association · 2025Trial
- Diagnostic Test Accuracy of Artificial Intelligence in Large Vessel Occlusion: A Systematic Review and Meta-Analysis.Neurology research international · 2026Review
- Machine learning enhanced noninvasive transcranial stroke detection using a portable eddy current damping sensor.iScience · 2025Article
- Utility of automated CT perfusion software in acute ischemic stroke with large and medium vessel occlusion.Annals of clinical and translational neurology · 2024Article
- Enhancing Stroke Recognition: A Comparative Analysis of Balance and Eyes-Face, Arms, Speech, Time (BE-FAST) and Face, Arms, Speech, Time (FAST) in Identifying Posterior Circulation Strokes.Journal of clinical medicine · 2024Article
- Diagnostic accuracy of large and medium vessel occlusions in acute stroke imaging by neurology residents and stroke fellows: A comparison of CT angiography alone and CT angiography with CT perfusion.European stroke journal · 2024Article
- Spatial CT perfusion data helpful in automatically locating vessel occlusions for acute ischemic stroke patients.Frontiers in neurology · 2023Article
- Practice enhancements with FastStroke ColorViz analysis in acute ischemic stroke.Journal of clinical imaging science · 2022Review
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Authors and funding
18 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEarly detection of large vessel occlusion (LVO) is essential to facilitate fast endovascular treatment. CT angiography (CTA) is used to detect LVO in suspected stroke patients. We aimed to assess the accuracy of CTA evaluations in daily clinical practice in a large cohort of suspected stroke patients. PATIENTS AND
methodsWe used data from the PRESTO study, a multicenter prospective observational cohort study that included suspected stroke patients between August 2018 and September 2019. Baseline CTAs were re-evaluated by an imaging core laboratory and compared to the local assessment. LVO was defined as an occlusion of the intracranial internal carotid artery, M1 segment, or basilar artery. Medium vessel occlusion (MeVO) was defined as an A1, A2, or M2 occlusion. We calculated the accuracy, sensitivity, and specificity to detect LVO and LVO+MeVO, using the core laboratory evaluation as reference standard.
resultsWe included 656 patients. The core laboratory detected 89 LVOs and 74 MeVOs in 155 patients. Local observers missed 6 LVOs (7%) and 28 MeVOs (38%), of which 23 M2 occlusions. Accuracy of LVO detection was 99% (95% CI: 98-100%), sensitivity 93% (95% CI: 86-97%), and specificity 100% (95% CI: 99-100%). Accuracy of LVO+MeVO detection was 95% (95% CI: 93-96%), sensitivity 79% (95% CI: 72-85%), and specificity 99% (95% CI: 98-100%). DISCUSSION AND
conclusionCTA evaluations in daily clinical practice are highly accurate and LVOs are adequately recognized. The detection of MeVOs seems more challenging. The evolving EVT possibilities emphasize the need to improve CTA evaluations in the acute setting.
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