Evidence map›Paper›PMID 35342700›Full record

ArticleGlobal heart2022

Adherence Clubs to Improve Hypertension Management in Nigeria: Clubmeds, a Feasibility Study.

Godsent C Isiguzo, Karla Santo, Rajmohan Panda, Lilian Mbau, Shiva R Mishra, Collins N Ugwu, Salim S Virani, Augustine N Odili, Emily R Atkins

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In one paragraph

Article in Global heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Godsent C IsiguzoAlex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Nigeria.ORCID 0000-0003-4661-6727
Karla SantoWestmead Applied Research Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0001-9047-8865
Rajmohan PandaPublic Health Foundation of India, New Delhi, India.ORCID 0000-0002-2385-3730
Lilian MbauKenya Cardiac Society, Nairobi, Kenya.ORCID 0000-0003-2086-4562
Shiva R MishraThe University of Queensland, Brisbane, Australia.ORCID 0000-0002-2993-3504
Collins N UgwuAlex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Nigeria.ORCID 0000-0002-8402-3407
Salim S ViraniMichael E. DeBakey Veterans Affairs Medical Center & Baylor College of Medicine, Houston, USA.ORCID 0000-0001-9541-6954
Augustine N OdiliCirculatory Health Research Laboratory, College of Health Sciences, University of Abuja, Abuja, Nigeria.ORCID 0000-0002-4564-1587
Emily R AtkinsWestmead Applied Research Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0003-2522-3510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertension control remains a significant challenge in reducing the cardiovascular disease burden worldwide. Community peer-support groups have been identified as a promising strategy to improve medication adherence and blood pressure (BP) control. Objectives: The study aimed to evaluate the feasibility and impact of adherence clubs to improve BP control in Southeast Nigeria. Methods: This was a mixed-methods research involving a formative (pre-implementation) research, pilot study and process evaluation. Hypertensive patients in two communities were recruited into peer-support adherence clubs under the leadership of role-model patients to motivate and facilitate medication adherence, BP monitoring, and monthly medication delivery for six months. The primary outcome was medication adherence measured using visual analogue scale (VAS), with BP level at six months as a key secondary outcome. Results: We recruited a total of 104 participants. The mean age was 56.8 (SD-10.7) years, 72 (69.2%) were women, mean BP was 146.7 (SD-20.1)/86.9 (SD-11.2) mmHg, and the mean percentage of medication adherence on the VAS was 41.4% (SD-11.9%). At six months, 67 patients were assessed; self-reported adherence on the VAS increased to 57.3% (SD-25.3%) (mean difference between baseline and follow-up of 15.5%, p < 0.0001), while the mean BP decreased to 132.3 (SD-22.0)/82.9 (SD-12.2) mmHg (mean difference of 13.0 mmHg in systolic BP, p < 0.0001 and of 3.6 mmHg in diastolic BP, p = 0.02). Five in-depth interviews and four focus groups discussions were conducted as part of the qualitative analyses of the study. The participants saw hypertension as a big issue, with many unaware of the diagnosis, and they accepted the CLUBMEDS differential service delivery (DSD) model concept in hypertension. Conclusions: The study demonstrates that the implementation of adherence clubs for hypertension control is feasible and led to a statistically significant and clinically meaningful improvement in self-reported medication adherence, resulting in BP reduction. Upscaling the intervention may be needed to confirm these findings.

Indexed as

HypertensionAntihypertensive AgentsBlood PressureFeasibility StudiesFemaleHumansMaleMedication AdherenceMiddle AgedNigeriaPilot ProjectsAntihypertensive Agentsadherence clubsAfricaBlood pressure-loweringmedicines accessprimary care

Identifiers

PMID35342700
PMCPMC8932363

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.