Evidence map›Paper›PMID 35342458›Full record

ArticleTherapeutic advances in musculoskeletal disease2022

Osteoporosis in 10 years time: a glimpse into the future of osteoporosis.

Giovanni Adami, Angelo Fassio, Davide Gatti, Ombretta Viapiana, Camilla Benini, Maria I Danila, Kenneth G Saag, Maurizio Rossini

Abstract read
In one paragraph

Article in Therapeutic advances in musculoskeletal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Romosozumab in patients who experienced an on-study fracture: post hoc analyses of the FRAME and ARCH phase 3 trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Trial
  3. Review
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  7. Bone Fragility: Time to Address the Matrix.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
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  12. Article
  13. The Positive Effects of Exercise on Adolescent Growth and Development.Advances in experimental medicine and biology · 2026
    Review
  14. Article
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  20. Clinical-radiomics nomogram construction from magnetic resonance imaging to diagnose osteoporosis: a preliminary study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giovanni AdamiRheumatology Unit, University of Verona, Pz Scuro 10, 37134 Verona, Italy.ORCID https://orcid.org/0000-0002-8915-0755
Angelo FassioRheumatology Unit, University of Verona, Verona, Italy.
Davide GattiRheumatology Unit, University of Verona, Verona, Italy.
Ombretta ViapianaRheumatology Unit, University of Verona, Verona, Italy.
Camilla BeniniRheumatology Unit, University of Verona, Verona, Italy.
Maria I DanilaDivision of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Kenneth G SaagDivision of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.ORCID https://orcid.org/0000-0001-6189-8078
Maurizio RossiniRheumatology Unit, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0001-9692-2293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients living with osteoporosis are projected to increase dramatically in the next decade. Alongside the forecasted increased societal and economic burden, we will live a crisis of fractures. However, we will have novel pharmacological treatment to face this crisis and, more importantly, new optimized treatment strategies. Fracture liaison services will be probably implemented on a large scale worldwide, helping to prevent additional fractures in high-risk patients. In the next decade, novel advances in the diagnostic tools will be largely available. Moreover, new and more precise fracture risk assessment tools will change our ability to detect patients at high risk of fractures. Finally, big data and artificial intelligence will help us to move forward into the world of precision medicine. In the present review, we will discuss the future epidemiology and costs of osteoporosis, the advances in early and accurate diagnosis of osteoporosis, with a special focus on biomarkers and imaging tools. Then we will examine new and refined fracture risk assessment tools, the role of fracture liaison services, and a future perspective on osteoporosis treatment.

Indexed as

bone mineral densityfracturesfuture perspectiveosteoporosis

Identifiers

PMID35342458
PMCPMC8941690

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.