Evidence map›Paper›PMID 35342425›Full record

ArticleInternational journal of dentistry2022

Effect of Preirradiation Fluoride Treatment on the Physical Properties of Dentin.

Francis K Mante, Aaron Kim, Kristi N Truong, Kriti Mittal, Spoorthi Alapati, Sarah Hagan, Jie Deng

Open access · goldAbstract read
In one paragraph

Article in International journal of dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Francis K ManteSchool of Dental Medicine, University of Pennsylvania, 240 South 40 Street, Philadelphia, PA 19104, USA.ORCID https://orcid.org/0000-0001-9656-9784
Aaron KimSchool of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kristi N TruongSchool of Dental Medicine, University of Pennsylvania, 240 South 40 Street, Philadelphia, PA 19104, USA.
Kriti MittalSchool of Dental Medicine, University of Pennsylvania, 240 South 40 Street, Philadelphia, PA 19104, USA.
Spoorthi AlapatiSchool of Dental Medicine, University of Pennsylvania, 240 South 40 Street, Philadelphia, PA 19104, USA.
Sarah HaganPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jie DengSchool of Nursing, University of Pennsylvania, Philadelphia, PA 19104, USA.
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine the effects of preirradiation fluoride treatments on the Knoop hardness of dentin. Materials and Methods: Human posterior teeth mounted into acrylic resin molds were polished with silicon carbide (SiC) abrasives and 3-micron diamond paste. The Knoop hardness of dentin was measured with a Leco hardness instrument. The teeth were divided into groups of ten teeth per group as follows: no treatment (control), treatment with silver diamine fluoride (SDF), MI varnish (MI), and cavity shield (CS). The teeth were exposed to 2 Gy of daily radiation for six weeks using an X-Rad 320ix biological irradiator. Hardness was measured weekly, before, during, and after irradiation. The teeth were stored in artificial saliva at 37 Results: In preirradiation dentin, a Knoop hardness value of 58.8 (14.1) KHN was obtained. Treatment with SDF significantly increased KHN before irradiation. Immediately after radiation treatment, hardness was significantly reduced in all experimental groups. Postirradiation fluoride treatments increased the hardness of dentin to varying degrees. Conclusions: Preirradiation fluoride treatment does not provide protection from decreases in the hardness of dentin. Treatment of teeth with fluoride formulations after radiation progressively restores the hardness of dentin to different degrees.

Identifiers

PMID35342425
PMCPMC8947862
OpenAlexW4220844584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.