Evidence map›Paper›PMID 35342364›Full record

ArticleInternational journal of biological sciences2022

Forsythoside A Mitigates Alzheimer's-like Pathology by Inhibiting Ferroptosis-mediated Neuroinflammation via Nrf2/GPX4 Axis Activation.

Chunyue Wang, Shanshan Chen, Hangyu Guo, Hongbo Jiang, Honghan Liu, Haoran Fu, Di Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

149 citing papers in PubMed, 277 citations in OpenAlex.

  1. Article
  2. Article
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  4. Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Review
  6. Antioxidants (Basel, Switzerland) · 2026
    Article
  7. Article
  8. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
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  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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  20. Article

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chunyue WangSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Shanshan ChenSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Hangyu GuoSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Hongbo JiangSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Honghan LiuSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Haoran FuSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Di WangSchool of Life Sciences, Jilin University, Changchun, 130012, China.
Jilin University · CNChangchun University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis and neuroinflammation play crucial roles in Alzheimer's disease (AD) pathophysiology. Forsythoside A (FA), the main constituent of

Indexed as

Alzheimer DiseaseFerroptosisAnimalsAnti-Inflammatory AgentsGlycosidesLipopolysaccharidesMaleMiceMice, TransgenicNeuroinflammatory DiseasesNF-E2-Related Factor 2Anti-Inflammatory AgentsforsythiasideGlycosidesLipopolysaccharidesNF-E2-Related Factor 2Alzheimer's diseaseferroptosisforsythoside AneuroinflammationneuroprotectionNrf2/GPX4 axis

Identifiers

PMID35342364
PMCPMC8935224
OpenAlexW4226064241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.