Evidence map›Paper›PMID 35342295›Full record

ReviewJournal of inflammation research2022

Insights into the Role of Commensal-Specific T Cells in Intestinal Inflammation.

Arne Gehlhaar, Ashwin Inala, Dhana Llivichuzhca-Loja, Tatiana N Silva, Comfort Y Adegboye, Amy E O'Connell, Liza Konnikova

Abstract readReview
In one paragraph

Review in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Role ofWorld journal of gastroenterology · 2024
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arne Gehlhaar *Department of Pediatrics, Yale University, New Haven, CT, USA.ORCID 0000-0001-8120-4942
Ashwin Inala *Department of Pediatrics, Yale University, New Haven, CT, USA.
Dhana Llivichuzhca-Loja *Department of Pediatrics, Yale University, New Haven, CT, USA.
Tatiana N Silva *Department of Pediatrics, Yale University, New Haven, CT, USA.
Comfort Y AdegboyeDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
Amy E O'ConnellDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
Liza KonnikovaDepartment of Pediatrics, Yale University, New Haven, CT, USA.ORCID 0000-0003-4804-5497

Funding

Function of T cells at the Maternal-Fetal InterfaceR01AI171980 · NIAID · YALE UNIVERSITY · PI Liza Konnikova · 2022 to 2026
$3.5M
The Role of Wnt2b in Intestinal HealthK08DK120871 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI OCONNELL, AMY E · 2020 to 2024
$896k
Repurposing Pharmacological Agents for Inherited Mast CellDisorders of the GutR21TR002639 · NCATS · YALE UNIVERSITY · PI GLOVER, SARAH C, HAMILTON, MATTHEW J · 2019 to 2020
$535k
Peripheral Immune Development in Premature Infants with and without NECR21HD102565 · NICHD · YALE UNIVERSITY · PI KONNIKOVA, LIZA, TSENG, GEORGE C. · 2020 to 2021
$456k
NCATS NIH HHS R21 TR002639NIAID NIH HHS R01 AI171980NICHD NIH HHS R21 HD102565NIDDK NIH HHS K08 DK120871
6 · The paper itself

Abstract

Trillions of microorganisms exist in the human intestine as commensals and contribute to homeostasis through their interactions with the immune system. In this review, we use previous evidence from published papers to elucidate the involvement of commensal-specific T cells (CSTCs) in regulating intestinal inflammatory responses. CSTCs are generated centrally in the thymus or peripherally at mucosal interfaces and present as CD4

Indexed as

commensalimmunitymicrobiomeT cells

Identifiers

PMID35342295
PMCPMC8943607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.