Evidence map›Paper›PMID 35342285›Full record

ArticleCancer informatics2022

Using Natural Language Processing Techniques to Detect Adverse Events From Progress Notes Due to Chemotherapy.

Yukinori Mashima, Takashi Tamura, Jun Kunikata, Shinobu Tada, Akiko Yamada, Masatoshi Tanigawa, Akiko Hayakawa, Hirokazu Tanabe, Hideto Yokoi

Abstract read
In one paragraph

Article in Cancer informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yukinori MashimaClinical Research Support Center, Kagawa University Hospital, Kagawa, Japan.ORCID https://orcid.org/0000-0002-7584-0157
Takashi TamuraPharmacoepidemiology & PMS Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Jun KunikataClinical Research Support Center, Kagawa University Hospital, Kagawa, Japan.ORCID https://orcid.org/0000-0002-0089-8311
Shinobu TadaInformation Network Administration Office, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Akiko YamadaDepartment of Medical Informatics, Kagawa University Hospital, Kagawa, Japan.
Masatoshi TanigawaDepartment of Medical Informatics, Kagawa University Hospital, Kagawa, Japan.ORCID https://orcid.org/0000-0003-2676-356X
Akiko HayakawaPharmacoepidemiology & PMS Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Hirokazu TanabePharmacoepidemiology & PMS Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Hideto YokoiClinical Research Support Center, Kagawa University Hospital, Kagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In recent years, natural language processing (NLP) techniques have progressed, and their application in the medical field has been tested. However, the use of NLP to detect symptoms from medical progress notes written in Japanese, remains limited. We aimed to detect 2 gastrointestinal symptoms that interfere with the continuation of chemotherapy-nausea/vomiting and diarrhea-from progress notes using NLP, and then to analyze factors affecting NLP. Materials and methods: In this study, 200 patients were randomly selected from 5277 patients who received intravenous injections of cytotoxic anticancer drugs at Kagawa University Hospital, Japan, between January 2011 and December 2018. We aimed to detect the first occurrence of nausea/vomiting (Group A) and diarrhea (Group B) using NLP. The NLP performance was evaluated by the concordance with a review of the physicians' progress notes used as the gold standard. Results: Both groups showed high concordance: 83.5% (95% confidence interval [CI] 74.1-90.1) in Group A and 97.7% (95% CI 91.3-99.9) in Group B. However, the concordance was significantly better in Group B ( Conclusion: We detected occurrences of nausea/vomiting and diarrhea accurately using NLP. However, there were more misdetection cases in Group A due to negative findings or past history, which may have been influenced by the physicians' more frequent documentation of nausea/vomiting.

Indexed as

data miningdrug-related side effects and adverse reactionsdrug therapyelectronic health recordsNatural language processingpharmacovigilanceprogress notes

Identifiers

PMID35342285
PMCPMC8943584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.