Evidence map›Paper›PMID 35342256›Full record

ArticleAnnals of Indian Academy of Neurology

Impact of the COVID-19 Pandemic on the Frequency, Clinical Spectrum and Outcomes of Pediatric Guillain-Barré Syndrome in India: A Multicentric Ambispective Cohort Study.

Divyani Garg, Rajinder K Dhamija, Aditya Choudhary, Ritu Shree, Sujit Kumar, Priyanka Samal, Abhishek Pathak, Pamidimukkala Vijaya, Yareeda Sireesha, Sruthi S Nair and 37 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

47 authors at 13 institutions in 1 country.

Divyani GargDepartment of Neurology, Lady Hardinge Medical College, New Delhi, India.
Rajinder K DhamijaDepartment of Neurology, Lady Hardinge Medical College, New Delhi, India.
Aditya ChoudharyDepartment of Neurology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
Ritu ShreeDepartment of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Sujit KumarDepartment of Neurology, Apollo Hospitals, Sheshadripuram, Bangalore, Karnataka, India.
Priyanka SamalKalinga Hospital Limited, Bhubaneswar, Odisha, India.
Abhishek PathakDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Pamidimukkala VijayaDepartment of Neurology, Lalitha Super Specialities Hospital Pvt. Ltd., Guntur, Andhra Pradesh, India.
Yareeda SireeshaDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Sruthi S NairDepartment of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Sanjay SharmaDepartment of Neurology, Ramakrishna Care Medical Sciences, Pvt Ltd, Raipur, Chhattisgarh, India.
Soaham DesaiDepartment of Neurology, Shree Krishna Hospital and Pramukhswami Medical College, Bhaikaka University, Karamsad, Anand, Gujarat, India.
Human P SinhaDepartment of Neurology, NH MMI Narayana Superspeciality Hospital, Raipur, Chattisgarh, India.
Ayush AgarwalDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Ashish UpadhyayDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
M V Padma SrivastavaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Rohit BhatiaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Awadh K PanditDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Rajesh K SinghDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Alisha ReyazDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
P M YogeeshDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Manish SalunkheDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Vivek LalDepartment of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Manish ModiDepartment of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Gagandeep SinghDepartment of Neurology, Dayanand Medical College, Ludhiana, Punjab, India.
Monika SinglaDepartment of Neurology, Dayanand Medical College, Ludhiana, Punjab, India.
Samhita PandaDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Maya GopalakrishnanDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Inder PuriDepartment of Neurology, Sardar Patel Medical College, Bikaner, Rajasthan, India.
Sudhir SharmaDepartment of Neurology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Bismay KumarDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Prashant K KushwahaDepartment of Neurology, NH MMI Narayana Superspeciality Hospital, Raipur, Chattisgarh, India.
Harshadkumar ChovatiyaDepartment of Neurology, Shree Krishna Hospital and Pramukhswami Medical College, Bhaikaka University, Karamsad, Anand, Gujarat, India.
Teresa FerreiraDepartment of Neurology, Goa Medical College, Goa, India.
Sanjeev K BhoiDepartment of Neurology, All India Institute of Medical Sciences, Bhubaneswar, Odissa, India.
Manish BhartiyaDepartment of Neurology, Army Hospital, Guwahati, Assam, India.
Subhash KaulDepartment of Neurology, Krishna Institute of Medical Sciences Hospital, Secunderabad, Telangana, India.
Anuja PatilDepartment of Neurology, Krishna Institute of Medical Sciences Hospital, Secunderabad, Telangana, India.
Neeharika L MathukumalliDepartment of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Madhu NagappaDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
P Praveen SharmaDepartment of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Aneesh BasheerDepartment of Medicine, Pondicherry Institute of Medical Sciences, Pondicherry, India.
Dileep RamachandranDepartment of Neurology, Government Medical College, Thiruvananthapuram, Kerala, India.
Neetha BalaramDepartment of Neurology, Government Medical College, Thiruvananthapuram, Kerala, India.
Jospeh SebastianDepartment of Neurology, Caritas Hospital, Kottayam, Kerala, India.
Venugopalan Y VishnuDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
GBS consortium
Lady Hardinge Medical College · INAll India Institute of Medical Sciences · INDayanand Medical College & Hospital · INGovernment Medical College · INShree Krishna Hospital · INAll India Institute of Medical Sciences Jodhpur · INApollo Hospitals · INBanaras Hindu University · INIndira Gandhi Medical College · INNational Institute of Mental Health and Neurosciences · INNizam's Institute of Medical Sciences · INPost Graduate Institute of Medical Education and Research · INSree Chitra Thirunal Institute for Medical Sciences and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study impact of COVID-19 pandemic on frequency, clinical/electrophysiological profile and treatment outcomes in pediatric Guillain-Barré syndrome (GBS). Background: GBS is the most frequent cause of pediatric acute flaccid paralysis. The effect of the COVID-19 pandemic on pediatric GBS is unclear in the literature. Methods: We conducted an ambispective, multicentric, cohort study involving 12 of 27 centres in GBS Consortium, during two periods: pre-COVID-19 (March-August 2019) and during COVID-19 (March-August 2020). Children ≤12 years who satisfied National Institute of Neurological Diseases and Stroke criteria for GBS/variants were enrolled. Details pertaining to clinical/laboratory parameters, treatment and outcomes (modified Rankin Scale (mRS) at discharge, GBS Disability score at discharge and 3 months) were analysed. Results: We enrolled 33 children in 2019 and 10 in 2020. Children in 2020 were older (median 10.4 [interquartile range 6.75-11.25] years versus 5 (2.5-8.4) years; Conclusions: The COVID-19 pandemic led to a marked decline in pediatric GBS presenting to hospitals. Antecedent illnesses, clinical and electrophysiological profile of GBS remained largely unchanged from the pre-pandemic era.

Indexed as

AIDPAMANCOVID-19Guillain–Barre syndromeIVIgSARS-CoV2

Identifiers

PMID35342256
PMCPMC8954314
OpenAlexW3214447547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.