Evidence map›Paper›PMID 35342131›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Severe Anemia Due to Cold Agglutinin Syndrome in a COVID-19 Patient with IgM Monoclonal Gammopathy of Undetermined Significance Successfully Treated with Corticosteroids.

Yutaka Tsukamoto, Masataka Umeda, Yuko Muto, Takashi Sugimoto, Momoko Yamauchi, Koji Ando, Koya Ariyoshi

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yutaka TsukamotoDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Japan.
Masataka UmedaDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Yuko MutoDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Japan.
Takashi SugimotoDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Japan.
Momoko YamauchiDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Japan.
Koji AndoDepartment of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, Japan.
Koya AriyoshiDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Japan.
Nagasaki University · JPHiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secondary cold agglutinin syndrome (CAS) is autoimmune hemolytic anemia secondary to infections and lymphoid disorder. We here report the first Asian case of CAS secondary to novel coronavirus disease 2019 (COVID-19). A 72-year-old Japanese woman presented with a 2-week history of dyspnea and cough, and laboratory data revealed severe hemolytic anemia with a hemoglobin level of 4.7 g/dL. She was diagnosed with COVID-19, CAS, and monoclonal gammopathy of undetermined significance (MGUS). The anemia responded to corticosteroids administered for COVID-19 and required maintenance therapy. Although corticosteroids are not a standard therapy for CAS, they might be effective for CAS secondary to COVID-19 complicated with MGUS.

Indexed as

Anemia, Hemolytic, AutoimmuneCOVID-19Monoclonal Gammopathy of Undetermined SignificanceAdrenal Cortex HormonesAgedCryoglobulinsFemaleHumansImmunoglobulin MAdrenal Cortex Hormonescold agglutininsCryoglobulinsImmunoglobulin Mautoimmune hemolytic anemiacold agglutinin syndromecorticosteroidCOVID-19monoclonal gammopathy of undetermined significance

Identifiers

PMID35342131
PMCPMC9259319
OpenAlexW4220954923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.