ArticleThe Science of the total environment2022
Variability in urinary concentrations of primary aromatic amines.
Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Intra-individual variability of urinary non-persistent chemical concentrations during pregnancy in the ECHO Cohort.Journal of exposure science & environmental epidemiology · 2026Article
- Prenatal exposure to aromatic amines and associations with infant cognition in the ECHO.CA.IL cohorts.Journal of exposure science & environmental epidemiology · 2026Article
- ToxBase: A Multidimensional ToxCast Reference Database for High-Throughput Human Exposome Analysis.Environmental science & technology · 2026Article
- p-Chloroaniline - Derivation of a BAR: Assessment Values in Biological Material - Translation of the German version from 2026.The MAK collection for occupational health and safety · 2026Review
- Review
- Synergistic azo reaction and electroextraction in SPME-SERS for direct determination of aromatic amines in biofluids with minimal matrix interference.Mikrochimica acta · 2025Article
- Environmental and dietary factors associated with urinary OH-PAHs in mid-pregnancy in a large multi-site study.Environmental research · 2025Article
- Occurrence of primary aromatic amines and nicotine in sediments collected from the United States.The Science of the total environment · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Despite their known carcinogenic potential, primary aromatic amines (AAs) continue to be used in various consumer products. Human exposure to AAs is a subject of current concern. Although urinary measurements are used in the assessment of exposure, little is known about within- and between-individual temporal variability in urinary concentrations of AAs. In this study, we determined the concentrations of 30 AAs, nicotine and cotinine in 213 first morning void (FMV) urine samples collected longitudinally for over a five-week period from 15 participants residing in the Albany area of New York State, USA. Eight AAs, namely, aniline, 2-naphthylamine (2-NA), p-cresidine (p-CD), p-toluidine (p-TD), o/m-toluidine (o/m-TD), 4-chloroaniline (4-CA), 4,4'-methylenedi-o-toluidine (4,4'-MDA), and 2,6-dimethylaniline (2,6-DMA) were found in urine at a detection frequency (DF) in the range of 68-100%. Aniline and 2,6-DMA were the predominant compounds found at median concentrations of 6.0 and 3.81 ng/mL, respectively. Intraclass correlation coefficients (ICCs) of all urinary AA concentrations, except for 4-CA, showed moderate to poor predictability (ICC values ranged 0.248-0.697). Gender and ethnicity-related variations in ∑
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