Evidence map›Paper›PMID 35341426›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2023

HEPA filtration intervention in classrooms may improve some students' asthma.

Stephen J Vesper, Larry Wymer, Brent A Coull, Petros Koutrakis, Amparito Cunningham, Carter R Petty, Nervana Metwali, William J Sheehan, Jonathan M Gaffin, Perdita Permaul and 6 more

Abstract read
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Indoor Allergen Interventions in Homes and Schools for Managing Asthma.The journal of allergy and clinical immunology. In practice · 2025
    Review
  4. The Impact of the Indoor Environment on Childhood Asthma.Current allergy and asthma reports · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. New considerations of health disparities within allergy and immunology.The Journal of allergy and clinical immunology · 2023
    Review
  9. Environmental Exposures Impact Pediatric Asthma Within the School Environment.Immunology and allergy clinics of North America · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Stephen J VesperUS Environmental Protection Agency, Center for Environmental Measurement and Modeling, Cincinnati, OH, USA.
Larry WymerUS Environmental Protection Agency, Center for Environmental Measurement and Modeling, Cincinnati, OH, USA.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0003-4118-6473
Amparito CunninghamDivision of Allergy and Immunology, Boston Children's Hospital, Boston, MA, USA.
Carter R PettyInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, USA.
Nervana MetwaliDepartment of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, IA, USA.
William J SheehanDivision of Allergy and Immunology, Boston Children's Hospital, Boston, MA, USA.
Jonathan M GaffinHarvard Medical School, Boston, MA, USA.
Perdita PermaulDivision of Pediatric Pulmonology, Allergy and Immunology, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA.
Peggy S LaiHarvard Medical School, Boston, MA, USA.
Lisa M BartnikasDivision of Allergy and Immunology, Boston Children's Hospital, Boston, MA, USA.
Marissa HauptmanHarvard Medical School, Boston, MA, USA.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Sachin M BaxiDivision of Allergy and Immunology, Boston Children's Hospital, Boston, MA, USA.
Wanda PhipatanakulDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Marc G Weisskopf · 1985 to 2026
$44.6M
SICAS- Diversity SupplementU01AI110397 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2015 to 2020
$8.8M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
ALLERGENS IN INNER-CITY SCHOOLS AND CHILDHOOD ASTHMAR01AI073964 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2008 to 2012
$4.6M
The school microbiome and asthma morbidity in inner-city childrenR01AI144119 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAI, PEGGY SUE · 2019 to 2023
$3.7M
Indoor Air Quality and Respiratory Morbidity in School-Aged Children with Bronchopulmonary DysplasiaR01ES030100 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2019 to 2023
$3.7M
Environmental Risk Factors for Pediatric Sleep Disordered BreathingR01HL137192 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2017 to 2020
$3.5M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
Atopy, Leptin and Potential Biomarkers of Comorbid Obesity and Asthma in Inner-City SchoolchildrenK23AI123517 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PERMAUL, PERDITA · 2017 to 2021
$1.1M
Air Pollution, Stress and Asthma Morbidity Risk: Role of Biological and Geospatial MarkersK23ES031663 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI HAUPTMAN, MARISSA · 2021 to 2025
$984k
Evaluating the Impact of School Nut-Free PoliciesK23AI143962 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI BARTNIKAS, LISA MARIE · 2019 to 2023
$970k
Role of Peanut Allergen in Urban Schools and PreschoolsK23AI104780 · NIAID · CHILDREN'S RESEARCH INSTITUTE · PI SHEEHAN, WILLIAM JAMES · 2014 to 2018
$912k
ATSDR CDC HHS R01 TS000296Intramural EPA EPA999999NHLBI NIH HHS R01 HL137192NHLBI NIH HHS U10 HL098102NIAID NIH HHS K23 AI104780NIAID NIH HHS K23 AI123517NIAID NIH HHS K23 AI143962NIAID NIH HHS K24 AI106822NIAID NIH HHS R01 AI073964NIAID NIH HHS R01 AI144119NIAID NIH HHS U01 AI110397NIEHS NIH HHS K23 ES031663NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES030100
6 · The paper itself

Abstract

objectiveThe School Inner-City Asthma Intervention Study 2 (SICAS 2) tested interventions to reduce exposures in classrooms of students with asthma. The objective of this

methodsPre-intervention dust samples were collected at the beginning of the school year from classrooms and corresponding homes of students with asthma (

resultsFor those students with a higher Group 1 mold level in their pre-intervention classroom than home (

conclusionsHEPA intervention in classrooms reduced Group 1 and ERMI values, which corresponded to improvements in the students' FEV1% test results.

Indexed as

Air Pollution, IndoorAsthmaDustFungiHousingHumansSpirometryDustdustERMIforced expiratory volumemoldSpirometry

Identifiers

PMID35341426
PMCPMC9548522

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.