Evidence map›Paper›PMID 35341319›Full record

ArticleStroke2022

Endovascular Treatment for Acute Ischemic Stroke With or Without General Anesthesia: A Matched Comparison.

Benjamin Wagner, Johannes Lorscheider, Andrea Wiencierz, Kristine Blackham, Marios Psychogios, Daniel Bolliger, Gian Marco De Marchis, Stefan T Engelter, Philippe Lyrer, Patrick R Wright and 17 more

Abstract read
In one paragraph

Article in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Benjamin Wagner *Department of Neurology (B.W., J.L., G.M.D.M., S.T.E., P.L., L.H.B.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0001-9330-1790
Johannes Lorscheider *Department of Neurology (B.W., J.L., G.M.D.M., S.T.E., P.L., L.H.B.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0003-1100-2506
Andrea WiencierzClinical Trial Unit (A.W., P.R.W.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0001-8786-7915
Kristine BlackhamInstitute of Diagnostic and Interventional Neuroradiology (K.B., M.P.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0002-1620-1144
Marios PsychogiosInstitute of Diagnostic and Interventional Neuroradiology (K.B., M.P.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0002-0016-414X
Daniel BolligerDepartment of Anesthesiology (D.B.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0003-4094-448X
Gian Marco De MarchisDepartment of Neurology (B.W., J.L., G.M.D.M., S.T.E., P.L., L.H.B.), University Hospital Basel and University of Basel, Switzerland.
Stefan T EngelterDepartment of Neurology (B.W., J.L., G.M.D.M., S.T.E., P.L., L.H.B.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0003-3855-6234
Philippe LyrerDepartment of Neurology (B.W., J.L., G.M.D.M., S.T.E., P.L., L.H.B.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0002-1435-1114
Patrick R WrightClinical Trial Unit (A.W., P.R.W.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0002-1153-0846
Urs FischerDepartment of Neurology (U.F., M.A.), Inselspital, Bern University Hospital, University of Bern, Switzerland.ORCID 0000-0003-0521-4051
Pasquale Mordasini
Stefania NannoniDepartment of Neurology, Lausanne University Hospital, Switzerland (S.N., F.P., P.M.).ORCID 0000-0002-1825-1874
Francesco PuccinelliDepartment of Neurology, Lausanne University Hospital, Switzerland (S.N., F.P., P.M.).
Timo KahlesDepartment of Neurology, Cantonal Hospital Aarau, Switzerland (T.K., K.N.).ORCID 0000-0002-1569-6376
Giovanni BiancoStroke Center EOC, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (G.B., C.W.C.).ORCID 0000-0003-0797-3668
Emmanuel CarreraDepartment of Neurology, University Hospital Geneva, Switzerland (E.C.).ORCID 0000-0003-0045-5382
Andreas R LuftDepartment of Neurology, University Hospital Zurich, Switzerland (A.R.L.).ORCID 0000-0001-9865-7382
Carlo W CeredaStroke Center EOC, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (G.B., C.W.C.).ORCID 0000-0002-6479-1476
Georg KägiDepartment of Neurology (G.K.), Cantonal Hospital St. Gallen, Switzerland.ORCID 0000-0001-7749-8060
Johannes WeberInstitute of Diagnostic and Interventional Neuroradiology (J.W.), Cantonal Hospital St. Gallen, Switzerland.ORCID 0000-0002-6106-3916
Krassen NedeltchevDepartment of Neurology, Cantonal Hospital Aarau, Switzerland (T.K., K.N.).
Patrik MichelInstitute of Diagnostic and Interventional Neuroradiology (P.M., J.G.), Inselspital, Bern University Hospital, University of Bern, Switzerland.ORCID 0000-0003-4954-7579
Jan GrallaInstitute of Diagnostic and Interventional Neuroradiology (P.M., J.G.), Inselspital, Bern University Hospital, University of Bern, Switzerland.
Marcel ArnoldDepartment of Neurology (U.F., M.A.), Inselspital, Bern University Hospital, University of Bern, Switzerland.
Leo H BonatiDepartment of Neurology (B.W., J.L., G.M.D.M., S.T.E., P.L., L.H.B.), University Hospital Basel and University of Basel, Switzerland.ORCID 0000-0003-1163-8133
Swiss Stroke Registry Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndovascular treatment in large artery occlusion stroke reduces disability. However, the impact of anesthesia type on clinical outcomes remains uncertain.

methodsWe compared consecutive patients in the Swiss Stroke Registry with anterior circulation stroke receiving endovascular treatment with or without general anesthesia (GA). The primary outcome was disability on the modified Rankin Scale after 3 months, analyzed with ordered logistic regression. Secondary outcomes included dependency or death (modified Rankin Scale score

resultsOne thousand two hundred eighty-four patients (GA: n=851, non-GA: n=433) from 8 Stroke Centers were included. Patients treated with GA had higher modified Rankin Scale scores after 3 months than patients treated without GA, in the unmatched (odds ratio [OR], 1.75 [1.42-2.16];

conclusionsThis large study showed worse functional outcome after endovascular treatment of anterior circulation stroke with GA than without GA in a real-world setting. This finding appears to be independent of known differences in patient characteristics between groups.

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeAnesthesia, GeneralHumansIntracranial HemorrhagesTreatment OutcomeUnited Statesanesthesia, generalintracranial hemorrhageischemic strokepropensity scoreregistries

Identifiers

PMID35341319
PMCPMC10082068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.