ArticleJournal of the American Chemical Society2022
Confronting the Challenging Asymmetric Carbonyl 1,2-Addition Using Vinyl Heteroarene Pronucleophiles: Ligand-Controlled Regiodivergent Processes through a Dearomatized Allyl-Cu Species.
Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 52 citations in OpenAlex.
- Force-modulated and strain-dependent stereoselectivity of copper-catalyzed reductive coupling.Chemical science · 2026Article
- Enantioselective Copper-Catalyzed Synthesis of Hydroxylamines via Hydrofunctionalization of Alkenes using Nitroalkanes.Journal of the American Chemical Society · 2026Article
- Asymmetric [3 + 2] Cycloaddition to Access 3-Pyrrolines and Their Switchable Transformations to Nine-Membered Cyclic Sulfamidates and 2H-Pyrroles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Catalytic Enantioselective Methods for Synthesis of 1,2-Amino Tertiary Alcohols and Their Analogues.Chemical reviews · 2025Review
- Cobalt-catalyzed reductive cross-coupling: a review.Molecular diversity · 2025Review
- Preparation of 1,4-Diamines by Enantio- and Diastereoselective Cu-Josiphos-Catalyzed Reductive Couplings of Azatrienes and Imines: Regiodivergence Enabled by Catalyst Structure and Reagent Tailoring.Journal of the American Chemical Society · 2025Article
- Stereodivergent synthesis of benzylic alcohol derivatives enabled by Pd/Cu co-catalyzed asymmetric benzylic substitution reaction.Nature communications · 2025Article
- CuH-Catalyzed Regio- and Enantioselective Formal Hydroformylation of Vinyl Arenes.Journal of the American Chemical Society · 2024Article
- Tunable C-H functionalization and dearomatization enabled by an organic photocatalyst.Chemical science · 2024Article
- Designed Iron Catalysts for Allylic C-H Functionalization of Propylene and Simple Olefins.Angewandte Chemie (International ed. in English) · 2023Article
- Formal nucleophilic pyrrolylmethylationChemical science · 2022Article
- Copper Hydride-Catalyzed Enantioselective Olefin Hydromethylation.Journal of the American Chemical Society · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The selective reductive coupling of vinyl heteroarenes with aldehydes and ketones represents a versatile approach for the rapid construction of enantiomerically enriched secondary and tertiary alcohols, respectively. Herein, we demonstrate a CuH-catalyzed regiodivergent coupling of vinyl heteroarenes with carbonyl-containing electrophiles, in which the selectivity is controlled by the ancillary ligand. This approach leverages an
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.