ArticleEvidence-based complementary and alternative medicine : eCAM2022
Combination Therapy with TCM Preparation Kumu Injection and Azithromycin against Bacterial Infection and Inflammation:
Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Yinhuapinggan granules regulate PI3K/AKT and RAS/MAPK pathways to inhibit Streptococcus Pneumoniae-induced inflammatory responses.Archives of microbiology · 2026Article
- Advances and mechanisms of traditional Chinese medicine and its active ingredients against antibiotic-resistantJournal of pharmaceutical analysis · 2025Review
- Progress in the study of chemical composition, biological activity, and its metabolism of theHeliyon · 2024Review
- Mechanism of Qiguiyin Decoction Sensitizing Levofloxacin Against Multidrug-ResistantInfection and drug resistance · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
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Abstract
Background: Azithromycin (AZM) is one of the most common broad-spectrum antibiotics. However, drug resistance is increasing and combination therapy has attracted great attention. AZM is usually combined with traditional Chinese medicine (TCM) preparations with heat-clearing and detoxifying effects, including Kumu injection (KM) made from Purpose: The present study aimed to investigate synergistic antimicrobial and anti-inflammatory activities of KM plus AZM with the aim of understanding the mechanism of clinical efficacy of combination regimens. Methods: Seven common bacterial clinical isolates and LPS-induced RAW 264.7 cells were used for assay of Results: KM-AZM combination synergistically inhibits Conclusion: KM-AZM combination displayed synergistic antibacterial and anti-inflammatory effects beneficial to the therapeutic potential against bacterial infection.
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Registered trials
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