Evidence map›Paper›PMID 35341136›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Liquiritin Attenuates Angiotensin II-Induced Cardiomyocyte Hypertrophy via ATE1/TAK1-JNK1/2 Pathway.

Jiajia Mo, Peng Zhou, Zhaoxing Chu, Yan Zhao, Xiang Wang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiajia MoHefei Industrial Pharmaceutical Institute Co., Ltd., Hefei, Anhui 230051, China.ORCID https://orcid.org/0000-0003-1259-219X
Peng ZhouAnhui University of Chinese Medicine, Hefei, Anhui 230012, China.ORCID https://orcid.org/0000-0002-7322-692X
Zhaoxing ChuHefei Industrial Pharmaceutical Institute Co., Ltd., Hefei, Anhui 230051, China.ORCID https://orcid.org/0000-0003-3347-7449
Yan ZhaoHefei Industrial Pharmaceutical Institute Co., Ltd., Hefei, Anhui 230051, China.ORCID https://orcid.org/0000-0001-9487-6043
Xiang WangAnhui University of Chinese Medicine, Hefei, Anhui 230012, China.ORCID https://orcid.org/0000-0002-2322-5988
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the protective effect and mechanism of liquiritin (LIQ) on cardiomyocyte hypertrophy induced by angiotensin II (Ang II). Methods: H9c2 cells were pretreated with LIQ before and after Ang II treatment. CCK8 assay was performed to evaluate cell viability. The cell surface area was measured by phalloidin staining. The mRNA expression of atrial and B-type natriuretic peptides (ANP and BNP, respectively) and Results: LIQ at a concentration of ≤30 Conclusion: LIQ can attenuate Ang II-induced cardiomyocyte hypertrophy by regulating the ATE1/TAK1-JNK1/2 pathway.

Identifiers

PMID35341136
PMCPMC8942629
OpenAlexW4220727633

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.