Evidence map›Paper›PMID 35341093›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2022

Rising syphilis rates in Canada, 2011-2020.

Josephine Aho, Cassandra Lybeck, Ashorkor Tetteh, Carmen Issa, Fiona Kouyoumdjian, Jason Wong, Alexandrea Anderson, Nashira Popovic

Open access · diamondAbstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
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  4. Uptake of prenatal syphilis screening and its determinants in Ontario, Canada: a population-based retrospective cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
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  13. Complete genome sequences of twoMicrobiology resource announcements · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Community and Hospital HIV Follow-Up Clinics Achieve Similar Lumbar Puncture and Syphilis Treatment Success in Patients with HIV-Syphilis Coinfection: Saskatoon, SK, Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025
    Article
  18. Canadian Public Health Laboratory Network National Syphilis In-Laboratory Serological Testing Recommendations.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Josephine AhoCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Cassandra LybeckCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Ashorkor TettehCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Carmen IssaCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Fiona KouyoumdjianOntario Ministry of Health, Toronto, ON.
Jason WongBC Centre for Disease Control, Vancouver, BC.
Alexandrea AndersonCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Nashira PopovicCentre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON.
Public Health Agency of Canada · CABC Centre for Disease Control · CAMinistry of Health and Long Term Care · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Syphilis rates are of public health concern in Canada, with multiple jurisdictions reporting outbreaks over the past five years. The objective of this article is to describe trends in infectious and congenital syphilis in Canada 2011-2020. Methods: Routine surveillance of syphilis is conducted through the Canadian Notifiable Disease Surveillance System (CNDSS). In response to rising rates of syphilis, all provinces and territories (P/Ts) have also submitted enhanced surveillance data on infectious syphilis to the Public Health Agency of Canada through the Syphilis Outbreak Investigation Coordinating Committee (SOICC) starting in 2018. Descriptive analyses of CNDSS and SOICC surveillance data 2011-2020 by age, sex, pregnancy status, male sexual orientation and P/Ts were performed. Results: The national rate of infectious syphilis increased from 5.1 per 100,000 population in 2011 to 24.7 per 100,000 population in 2020.The rates increased in almost all P/Ts, with the Prairie provinces reporting the greatest relative increases from 2016 to 2020 (more than 400%). Rates in males were consistently higher than rates in females over the past 10 years; however, from 2016 to 2020, rates among females increased by 773%, compared with 73% among males. Although the proportion of cases who self-identify as gay, bisexual and other men who have sex with men decreased from 54% to 38% between 2018 and 2020, they still represent a high proportion of cases (according to data from eight P/Ts). From 2016 to 2020, rates of infectious syphilis increased in every age group, especially in females aged 15-39 years. Confirmed early congenital syphilis cases for 2020 increased considerably from prior years, with 50 cases reported in 2020, compared with 4 cases in 2016. Conclusion: Infectious and congenital syphilis rates are a growing concern in Canada and the nature of the syphilis epidemics across Canada appears to be evolving, as evidenced by recent trends. More data and research are needed to better understand the drivers associated with the recent changes in the epidemiology of syphilis in Canada.

Indexed as

Canadacongenital syphilisgbMSMheterosexual femalesinfectious syphilispregnant individualssurveillance

Identifiers

PMID35341093
PMCPMC8889924
OpenAlexW4214648207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.