Evidence map›Paper›PMID 35341016›Full record

ReviewFrontiers in neuroscience2022

Looking for "fNIRS Signature" in Autism Spectrum: A Systematic Review Starting From Preschoolers.

Eugenia Conti, Elena Scaffei, Chiara Bosetti, Viviana Marchi, Valeria Costanzo, Valerio Dell'Oste, Raffaele Mazziotti, Liliana Dell'Osso, Claudia Carmassi, Filippo Muratori and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. What are quantitative traits and how can they be used in autism research?Autism research : official journal of the International Society for Autism Research · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Eugenia ContiDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Elena ScaffeiDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Chiara BosettiDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Viviana MarchiDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Valeria CostanzoDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Valerio Dell'OsteDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Raffaele MazziottiDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Liliana Dell'OssoDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Claudia CarmassiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Filippo MuratoriDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Laura BaroncelliDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Sara CalderoniDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Roberta BattiniDepartment of Developmental Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.
Fondazione Stella Maris · ITUniversity of Pisa · ITNational Research Council · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence suggests that functional Near-Infrared Spectroscopy (fNIRS) can provide an essential bridge between our current understanding of neural circuit organization and cortical activity in the developing brain. Indeed, fNIRS allows studying brain functions through the measurement of neurovascular coupling that links neural activity to subsequent changes in cerebral blood flow and hemoglobin oxygenation levels. While the literature offers a multitude of fNIRS applications to typical development, only recently this tool has been extended to the study of neurodevelopmental disorders (NDDs). The exponential rise of scientific publications on this topic during the last years reflects the interest to identify a "fNIRS signature" as a biomarker of high translational value to support both early clinical diagnosis and treatment outcome. The purpose of this systematic review is to describe the updating clinical applications of fNIRS in NDDs, with a specific focus on preschool population. Starting from this rationale, a systematic search was conducted for relevant studies in different scientific databases (Pubmed, Scopus, and Web of Science) resulting in 13 published articles. In these studies, fNIRS was applied in individuals with Autism Spectrum Disorder (ASD) or infants at high risk of developing ASD. Both functional connectivity in resting-state conditions and task-evoked brain activation using multiple experimental paradigms were used in the selected investigations, suggesting that fNIRS might be considered a promising method for identifying early quantitative biomarkers in the autism field.

Indexed as

autism spectrum disorderfNIRSfunctional neuroimaginghigh-risk infantnear-infrared spectroscopyneurodevelopmental disorderspreschooler

Identifiers

PMID35341016
PMCPMC8948464
OpenAlexW4214926882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.