Evidence map›Paper›PMID 35341010›Full record

ArticleComputational and mathematical methods in medicine2022

Liuwei Dihuang Pill Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis via TGF-

Shi Shu, Yue Zhang, Qian Wang, Pengyu Tao, Zhijie Li, Zhongju Xu, Haiying Lu, Lin Shi

RetractedAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Shi ShuShanghai Punan Hospital of Pudong New District, Shanghai 200125, China.
Yue ZhangBasic Medical School, Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China.
Qian WangPostdoctoral Workstation, Department of Central Laboratory, The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China.ORCID https://orcid.org/0000-0002-5031-0686
Pengyu TaoBasic Medical School, Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China.
Zhijie LiScience and Technology Center, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhongju XuShanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 200052, China.
Haiying LuNursing School, Shanghai University of Traditional Chinese Medicine, Shanghai 200120, China.
Lin ShiDepartment of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221004 Jiangsu Province, China.ORCID https://orcid.org/0000-0002-2477-839X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among all the complications of diabetes, diabetic nephropathy is a significant factor causing the end-stage renal disease associated with high death rates. Current treatment fails to produce an ideal outcome. Thus, searching for a new preventive drug is urgently needed. Liuwei Dihuang pill (LDP), a popular ancient Chinese medicine (TCM) prescription, has been applied to treat DN-like syndromes according to TCM theory. Here, we had established an animal model with DN and LDP therapy was put into use to assess its therapeutic effect in vivo. Our data showed that oxidative stress and TGF-

Indexed as

Diabetes MellitusDiabetic NephropathiesAnimalsFibrosisKidneyMiceSignal TransductionSmad2 ProteinTransforming Growth Factor betaSmad2 ProteinSMAD2 protein, humanTransforming Growth Factor beta

Identifiers

PMID35341010
PMCPMC8941499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.