Evidence map›Paper›PMID 35340875›Full record

ArticleExperimental and therapeutic medicine2022

Prognostic factors for the safety and efficacy of retrograde laser lithotripsy: Data from a contemporary series of 155 consecutive patients with single and multiple lithiasis of the urinary tract.

Diomidis Kozyrakis, Georgios Soukias, Dimitrios Karagiannis, Anastasios Zarkadas, Stefanos Perikleous, Styliani-Elissavet Chatzistamou, Ilias Katsaros, Konstantinos Skriapas, Michael Lardas, Nikolaos Mertziotis and 1 more

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Article in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Diomidis KozyrakisDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Georgios SoukiasDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Dimitrios KaragiannisDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Anastasios ZarkadasDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Stefanos PerikleousDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Styliani-Elissavet ChatzistamouDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Ilias KatsarosDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Konstantinos SkriapasDepartment of Urology, General Hospital of Larisa, Larisa 41447, Greece.
Michael LardasDepartment of Urology, 'Metropolitan' General Hospital, Athens 15562, Greece.
Nikolaos MertziotisDepartment of Urology, 'Metropolitan' General Hospital, Athens 15562, Greece.
Zisis KratirasDepartment of Urology, 'Achillopoulio' General Hospital, Volos 32222, Greece.
Agios Pavlos General Hospital · GRMetropolitan Hospital · GR404 General Military Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of large and multiple stones located in the ureter and/or the kidney may be challenging. The aim of the current study was to evaluate the results and complications of retrograde endoscopic lithotripsy for stones located in the urinary tract and to determine prognostic factors for treatment outcome. From April 2017 to March 2020, eligible patients for the active treatment of ureterolithiasis with or without concomitant nephrolithiasis <20 mm were enrolled in the study. The prognostic factors for the stone free rate (SFR) after the 1st and subsequent sessions and overall complications were assessed. Patients were divided into single or multiple lithiasis groups (groups A and B respectively). A comparison between these two groups was then conducted. Overall, 237 stones were detected in 155 patients, representing a mean burden of 1.53 stone per patient. The mean total stone size was 14.7 mm, the initial SFR was 80% and the final SFR (after a mean of 1.23 session per patient) was 94.2%. The rate of complications was 26.4%. Multivariative analysis revealed that preoperative stenting and total stone size were independent prognostic factors of initial SFR, while no independent factors were determined for final SFR. Age, total size and stones in the lower calyx were independent factors for complications. In group A and B, 114 and 41 cases with solitary and multiple stones were included, respectively. Excluding operation time (P=0.002), no significant differences were recorded in terms of initial (P=0.255) and final SFR (P=0.056), hospital stay (P=0.308), mean number of treatments (P=0.757) and the rate of complications (P=0.218) between the two groups. In conclusion, retrograde endoscopic management of multiple lithiasis has a favorable outcome irrespective of stone location. Older patients with higher burdens and stones in the lower calyx should be treated with caution.

Indexed as

lithotripsymultiple stonesnephrolithiasisstone freeureterolithiasis

Identifiers

PMID35340875
PMCPMC8931596
OpenAlexW4213234463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.