ArticleExperimental and therapeutic medicine2022
Application of machine learning tools: Potential and useful approach for the prediction of type 2 diabetes mellitus based on the gut microbiome profile.
Article in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Artificial Intelligence-Driven Food Safety: Decoding Gut Microbiota-Mediated Health Effects of Non-Microbial Contaminants.Foods (Basel, Switzerland) · 2025Review
- Specification curve analysis of the TEDDY study reveals large variation in microbiome-based T1D predictive performance.Nature communications · 2025Article
- DRPM: An advanced predictive model for early diabetes detection and risk stratification.Molecular therapy. Nucleic acids · 2025Article
- Chronological age estimation from human microbiomes with transformer-based Robust Principal Component Analysis.Communications biology · 2025Article
- Leveraging innovative diagnostics as a tool to contain superbugs.Antonie van Leeuwenhoek · 2025Review
- Distinct gut microbial species, but not phylum-to-genus composition, associate with insulin resistance: a unique perspective from the Kazakh population.Frontiers in microbiology · 2025Article
- Methodology for biomarker discovery with reproducibility in microbiome data using machine learning.BMC bioinformatics · 2024Article
- From-Toilet-to-Freezer: A Review on Requirements for an Automatic Protocol to Collect and Store Human Fecal Samples for Research Purposes.Biomedicines · 2023Review
- Pharmacomicrobiomics and type 2 diabetes mellitus: A novel perspective towards possible treatment.Frontiers in endocrinology · 2023Review
- Dysbiosis signatures of gut microbiota and the progression of type 2 diabetes: a machine learning approach in a Mexican cohort.Frontiers in endocrinology · 2023Article
- Multi-omics approaches to studying gastrointestinal microbiome in the context of precision medicine and machine learning.Frontiers in molecular biosciences · 2023Review
- Gut-Microbiome Interactions: Characterization, Therapeutic Implications and Machine Learning.Sage open pathologyReview
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota plays an important role in the regulation of the immune system and the metabolism of the host. The aim of the present study was to characterize the gut microbiota of patients with type 2 diabetes mellitus (T2DM). A total of 118 participants with newly diagnosed T2DM and 89 control subjects were recruited in the present study; six clinical parameters were collected and the quantity of 10 different types of bacteria was assessed in the fecal samples using quantitative PCR. Taking into consideration the six clinical variables and the quantity of the 10 different bacteria, 3 predictive models were established in the training set and test set, and evaluated using a confusion matrix, area under the receiver operating characteristic curve (AUC) values, sensitivity (recall), specificity, accuracy, positive predictive value and negative predictive value (npv). The abundance of
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