ReviewChemical science2022
Pd-catalysed C-H functionalisation of free carboxylic acids.
Review in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 67 citations in OpenAlex.
- Alkyl-to-Alkyl Palladium Migration Enables Remote C-C Bond Formation.Journal of the American Chemical Society · 2026Article
- Two-dimensional Pd-C bonded organometallic framework with dynamic packing transformations.Chemical science · 2026Article
- Transition Metal-Catalyzed Direct C(spChemical reviews · 2026Review
- Ligand-Controlled Alkylation-Heck-C(spJournal of the American Chemical Society · 2025Article
- Direct Pd-Catalyzed β-C(spOrganic letters · 2025Article
- Pd/C promotes C-H bond activation and oxidation of p-hydroxybenzoate during hydrogenolysis of poplar.Nature communications · 2025Article
- Tandem dehydrogenation-olefination-decarboxylation of cycloalkyl carboxylic acids via multifold C-H activation.Nature communications · 2024Article
- Iodoarene-directed photoredox β-C(spChemical science · 2024Article
- Highly Enantioselective Catalytic Lactonization at Nonactivated Primary and SecondaryJournal of the American Chemical Society · 2023Article
- Article
- C-H Glycosylation of Native Carboxylic Acids: Discovery of Antidiabetic SGLT-2 Inhibitors.ACS central science · 2023Article
- DistalChemical science · 2023Article
- Facile HFrontiers in chemistry · 2023Article
- Carboxylic Acid Directed γ-Lactonization of Unactivated Primary C-H Bonds Catalyzed by Mn Complexes: Application to Stereoselective Natural Product Diversification.Journal of the American Chemical Society · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pd-catalysed C-H functionalisation of free carboxylic acids has drawn significant attention over the last few years due to the predominance of carboxylic acid moieties in pharmaceuticals and agrochemicals. But their coordinating ability was overlooked and masked by exogenous directing groups for a long time. Even other crucial roles of carboxylic acids as additives and steric inducers that directly influence the mode of a reaction have been widely neglected. This review aims to embrace all of the diverse aspects of carboxylic acids except additive and steric effects by concisely and systematically describing their versatile role in Pd-catalysed proximal and distal C-H activation reactions that could be implemented in the pharmaceutical and agrochemical industries. In addition, the mechanistic perspectives along with several recent strategies developed in the last few years discussed here will serve as educational resources for future research.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.