Evidence map›Paper›PMID 35340839›Full record

ArticleFrontiers in bioengineering and biotechnology2022

A Versatile Pep-CPDs Nanoprobe for Rapid Detection of mTBI Biomarker in Clinical Instances and Safe Fluorescence Imaging

Jian Shi, Xingmei Li, María José Cavagnaro, Jifeng Cai, Changquan Zhang, Na Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jian ShiCenter for Experimental Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Xingmei LiDepartment of Forensic Science, School of Basic Medical Sciences, Central South University, Changsha, China.
María José CavagnaroCollege of Medicine-Phoenix, University of Arizona, Phoenix, AZ, United States.
Jifeng CaiDepartment of Forensic Science, School of Basic Medical Sciences, Central South University, Changsha, China.
Changquan ZhangDepartment of Forensic Science, School of Basic Medical Sciences, Central South University, Changsha, China.
Na LiDepartment of Radiology, The Third Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNThird Xiangya Hospital · CNUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild traumatic brain injury (mTBI) is the most common form of traumatic brain injury; however, it is the most difficult to be accurately identified in the early stage because it lacks more reliable biomarkers and detection methods. This study proposes a highly efficient system to detect a molecular biomarker for the early diagnosis of mTBI. The system was prepared by a lower cytotoxic peptide-modified fluorescent nanoprobe based on carbon polymer dots (pep-CPDs) with outstanding imaging capabilities.

Indexed as

bioimagingcarbon polymer dotsearly-warning strategyfluorescent imagingmild traumatic brain injurynon-toxic biosensorsTBI biomarkersversatile functionalized biomaterial

Identifiers

PMID35340839
PMCPMC8942774
OpenAlexW4220827093

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.