Evidence map›Paper›PMID 35340827›Full record

ArticleEuropean journal of radiology open2022

Increased MR-guided high intensity focused ultrasound (MR-HIFU) sonication efficiency of uterine fibroids after carbetocin administration.

Kimberley J Anneveldt, Heleen J van 't Oever, Inez M Verpalen, Ingrid M Nijholt, Wilbert Bartels, Jeroen R Dijkstra, Rolf D van den Hoed, Miranda van 't Veer-Ten Kate, Erwin de Boer, Sebastiaan Veersema and 3 more

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In one paragraph

Article in European journal of radiology open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Kimberley J AnneveldtDepartment of Radiology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Heleen J van 't OeverDepartment of Emergency Healthcare, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Inez M VerpalenDepartment of Radiology, Amsterdam University Medical Center, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Ingrid M NijholtDepartment of Radiology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Wilbert BartelsImage Sciences Institute, Imaging Division, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Jeroen R DijkstraDepartment of Gynecology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Rolf D van den HoedDepartment of Radiology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Miranda van 't Veer-Ten KateDepartment of Radiology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Erwin de BoerDepartment of Radiology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Sebastiaan VeersemaDepartment of Reproductive Medicine and Gynecology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Judith A F HuirneDepartment of Obstetrics and Gynecology and Amsterdam research institute Reproduction and Development, Amsterdam University Medical Centre, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Joke M SchutteDepartment of Gynecology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Martijn F BoomsmaDepartment of Radiology, Isala hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Isala · NLUniversity Medical Center Utrecht · NLUniversity Medical Center · USUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We investigated whether administration of the long-acting uterus stimulant carbetocin increased intra-subject sonication efficiency during Magnetic Resonance image guided High Intensity Focused Ultrasound (MR-HIFU) treatment of uterine fibroids. Method: In this prospective cohort study, thirty women with symptomatic uterine fibroids undergoing MR-HIFU treatment were included between January 2018 and January 2019. Treatment started with three sonications on one side of the uterine fibroid. Subsequently, one ampoule of 1 mL carbetocin (100 µg/mL) was administered intravenously and treatment continued with three sonications on the other side of the uterine fibroid. We compared the intra-subject sonication efficiency, in terms of Energy Efficiency Factor (EEF), thermal dose volume and sonication time to ablate one cm Results: Sonication efficiency improved after carbetocin administration as indicated by a significant decrease in EEF and sonication time (p = 0.006 and p = 0.001 respectively), and a significant increase in thermal dose volume reached (p = <0.001). Five women (16.7%) experienced temporary tachycardia, one women in combination with headache, within 30 min after carbetocin administration. Conclusion: Administration of the long-acting uterus stimulant carbetocin improved the MR-HIFU treatment intra-subject sonication efficiency in women with symptomatic uterine fibroids.

Indexed as

EEF, Energy Efficiency FactorEfficiencyEM, Equivalent MinutesHigh-intensity focused ultrasound ablationMaSS, Myoma Screening StudyMR guided interventional proceduresMR-HIFU, Magnetic Resonance image guided High Intensity Focused UltrasoundMyomaNPV, Non-Perfused VolumeSI, Signal IntensitySSI, Scaled Signal IntensityT1w-CE, Contrast-enhanced T1-weighted imagingT2w, T2-weighted imagingUterine fibroidsUterus stimulant

Identifiers

PMID35340827
PMCPMC8942847
OpenAlexW4220687584

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.