Evidence map›Paper›PMID 35340570›Full record

ArticleOptica2022

Deep-learning based image reconstruction for MRI-guided near-infrared spectral tomography.

Jinchao Feng, Wanlong Zhang, Zhe Li, Kebin Jia, Shudong Jiang, Hamid Dehghani, Brian W Pogue, Keith D Paulsen

Open access · goldAbstract read
In one paragraph

Article in Optica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  15. Quantitative molecular bioluminescence tomography.Journal of biomedical optics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Jinchao FengBeijing Key Laboratory of Computational Intelligence and Intelligent System, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China.
Wanlong ZhangBeijing Key Laboratory of Computational Intelligence and Intelligent System, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China.
Zhe LiBeijing Key Laboratory of Computational Intelligence and Intelligent System, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China.ORCID 0000-0002-8972-8609
Kebin JiaBeijing Key Laboratory of Computational Intelligence and Intelligent System, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China.
Shudong JiangThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.ORCID 0000-0001-7396-7886
Hamid DehghaniSchool of Computer Science, University of Birmingham, Birmingham, B15 2TT, UK.ORCID 0000-0003-4117-0412
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.ORCID 0000-0002-9887-670X
Keith D PaulsenThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.
Dartmouth College · USBeijing University of Technology · CNUniversity of Birmingham · GB

Funding

Concurrent Optical Spectroscopy and Breast MRI to Improve Diagnosis without Contrast InjectionR01EB027098 · NIBIB · DARTMOUTH COLLEGE · PI Shudong Jiang, KEITH D. PAULSEN · 2019 to 2026
$3.3M
Monitoring Neoadjuvant Chemotherapy Responses with NIR TomographyR01CA176086 · NCI · DARTMOUTH COLLEGE · PI JIANG, SHUDONG · 2014 to 2018
$2.0M
NCI NIH HHS R01 CA176086NIBIB NIH HHS R01 EB027098
6 · The paper itself

Abstract

Non-invasive near-infrared spectral tomography (NIRST) can incorporate the structural information provided by simultaneous magnetic resonance imaging (MRI), and this has significantly improved the images obtained of tissue function. However, the process of MRI guidance in NIRST has been time consuming because of the needs for tissue-type segmentation and forward diffuse modeling of light propagation. To overcome these problems, a reconstruction algorithm for MRI-guided NIRST based on deep learning is proposed and validated by simulation and real patient imaging data for breast cancer characterization. In this approach, diffused optical signals and MRI images were both used as the input to the neural network, and simultaneously recovered the concentrations of oxy-hemoglobin, deoxy-hemoglobin, and water via end-to-end training by using 20,000 sets of computer-generated simulation phantoms. The simulation phantom studies showed that the quality of the reconstructed images was improved, compared to that obtained by other existing reconstruction methods. Reconstructed patient images show that the well-trained neural network with only simulation data sets can be directly used for differentiating malignant from benign breast tumors.

Identifiers

PMID35340570
PMCPMC8952193
OpenAlexW4206017534

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.