Evidence map›Paper›PMID 35340410›Full record

ArticleDisease markers2022

HSPB1 Gene Variants and Schizophrenia: A Case-Control Study in a Polish Population.

Malgorzata Kowalczyk, Krzysztof Kucia, Aleksander Owczarek, Renata Suchanek-Raif, Monika Paul-Samojedny, Piotr Choreza, Jan Kowalski

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Malgorzata KowalczykDepartment of Medical Genetics, School of Pharmaceutical Sciences, Medical University of Silesia, Jednosci 8, 41-200 Sosnowiec, Poland.ORCID https://orcid.org/0000-0001-6679-1368
Krzysztof KuciaDepartment of Psychiatry and Psychotherapy, School of Medical Sciences, Medical University of Silesia, Katowice, Ziolowa 45, 40-635 Katowice, Poland.ORCID https://orcid.org/0000-0001-5618-2833
Aleksander OwczarekHealth Promotion and Obesity Management Unit, Department of Pathophysiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Medykow 15, 40-752 Katowice, Poland.ORCID https://orcid.org/0000-0003-1179-6932
Renata Suchanek-RaifDepartment of Medical Genetics, School of Pharmaceutical Sciences, Medical University of Silesia, Jednosci 8, 41-200 Sosnowiec, Poland.ORCID https://orcid.org/0000-0002-6836-6127
Monika Paul-SamojednyDepartment of Medical Genetics, School of Pharmaceutical Sciences, Medical University of Silesia, Jednosci 8, 41-200 Sosnowiec, Poland.ORCID https://orcid.org/0000-0002-4685-1674
Piotr ChorezaDivision of Statistics, Department of Instrumental Analysis, School of Pharmaceutical Sciences, Medical University of Silesia, Ostrogorska 30, 41-200 Sosnowiec, Poland.ORCID https://orcid.org/0000-0002-1745-4821
Jan KowalskiDepartment of Medical Genetics, School of Pharmaceutical Sciences, Medical University of Silesia, Jednosci 8, 41-200 Sosnowiec, Poland.ORCID https://orcid.org/0000-0001-6455-4502
Medical University of Silesia · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia (SCZ) is a severe psychiatric disorder that has a significant genetic component. HSPB1 (HSP27) is known for its neuroprotective functions under stress conditions and appears to play an important role during the development of the central nervous system, which is in agreement with the neurodevelopmental hypothesis of SCZ. The aim of the present case-control study was to investigate whether

Indexed as

SchizophreniaCase-Control StudiesGenetic Predisposition to DiseaseGenotypeHeat-Shock ProteinsHSP27 Heat-Shock ProteinsHumansMolecular ChaperonesPolandPolymorphism, Single NucleotideHeat-Shock ProteinsHSP27 Heat-Shock ProteinsHSPB1 protein, humanMolecular Chaperones

Identifiers

PMID35340410
PMCPMC8941579
OpenAlexW4220859712

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.