Evidence map›Paper›PMID 35340208›Full record

ArticleOxidative medicine and cellular longevity2022

1,25(OH)

Jun-Wu Wang, Lei Zhu, Peng-Zhi Shi, Ping-Chuan Wang, Yan Dai, Yong-Xiang Wang, Xu-Hua Lu, Xiao-Fei Cheng, Xin-Min Feng, Liang Zhang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jun-Wu WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.ORCID https://orcid.org/0000-0002-3553-4390
Lei ZhuDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
Peng-Zhi ShiGraduate School of Dalian Medical University, Dalian 116000, China.
Ping-Chuan WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
Yan DaiMedical Experimental Research Center, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
Yong-Xiang WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.
Xu-Hua LuDepartment of Orthopedics, Changzheng Hospital of The Second Military Medical University, Shanghai 200003, China.
Xiao-Fei ChengDepartment of Orthopedic Surgery, Shanghai Key Laboratory of Orthopedics Implants, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China.
Xin-Min FengDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.ORCID https://orcid.org/0000-0001-9287-858X
Liang ZhangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.ORCID https://orcid.org/0000-0001-7561-1488
Yangzhou University · CNDalian Medical University · CNSecond Military Medical University · CNShanghai Ninth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intervertebral disc degeneration (IVDD) is one of the main causes of low back pain. The local environment of the degenerated intervertebral disc (IVD) increases oxidative stress and apoptosis of endogenous nucleus pulposus-derived mesenchymal stem cells (NPMSCs) and weakens its ability of endogenous repair ability in degenerated IVDs. A suitable concentration of 1

Indexed as

Mesenchymal Stem CellsNucleus PulposusAnimalsHydrogen PeroxideOxidative StressPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleyHydrogen PeroxidePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt

Identifiers

PMID35340208
PMCPMC8956384
OpenAlexW4220665035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.