Evidence map›Paper›PMID 35339817›Full record

ArticleVeterinary microbiology2022

Experimental veterinary SARS-CoV-2 vaccine cross neutralization of the Delta (B.1.617.2) variant virus in cats.

Ashley Hoyte, Mark Webster, Keith Ameiss, Douglas A Conlee, Nicole Hainer, Kendra Hutchinson, Yulia Burakova, Paul J Dominowski, Eric T Baima, Vickie L King and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Veterinary microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Ashley HoyteZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: Ashley.hoyte@zoetis.com.
Mark WebsterZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: mark.webster@zoetis.com.
Keith AmeissZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: keith.ameiss@zoetis.com.
Douglas A ConleeZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: douglas.conlee@zoetis.com.
Nicole HainerZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: Nicole.hainer@zoetis.com.
Kendra HutchinsonZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: Kendra.hutchinson@zoetis.com.
Yulia BurakovaZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: Yulia.burakova@zoetis.com.
Paul J DominowskiZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: paul.j.dominowski@zoetis.com.
Eric T BaimaZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: eric.t.baima@zoetis.com.
Vickie L KingZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: Vickie.l.king@zoetis.com.
Everett L RoseyZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: everett.rosey@zoetis.com.
John M HardhamZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: john.m.hardham@zoetis.com.
Jason MillershipZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: jason.millership@zoetis.com.
Mahesh KumarZoetis Inc., Parisppany, NJ 07054, USA. Electronic address: Mahesh.kumar@zoetis.com.
Zoetis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 has exhibited varying pathogenesis in a variety of Mammalia family's including Canidae, Mustelidae, Hominidae, Cervidae, Hyaenidae, and Felidae. Novel SARS-CoV-2 variants characterized by spike protein mutations have recently resulted in clinical and epidemiological concerns, as they potentially have increased infectious rates, increased transmission, or reduced neutralization by antibodies produced via vaccination. Many variants have been identified at this time, but the variant of continuing concern has been the Delta variant (B.1.617.2), due to its increased transmissibility and infectious rate. Felines vaccinated using an experimental SARS-CoV-2 spike protein-based veterinary vaccine mounted a robust immune response to the SARS-CoV-2 spike protein. Using a reporter virus particle system and feline serum, we have verified that vaccinated felines produce antibodies that neutralize the SARS-CoV-2 Wuhan strain and variant B.1.617.2 at comparable levels.

Indexed as

Cat DiseasesCOVID-19FelidaeAnimalsAntibodies, NeutralizingAntibodies, ViralCatsCOVID-19 VaccinesSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2B.1.617.2CanineCanine vaccineCat vaccineDeltaDelta variantMinkMink vaccineSARS-CoV-2Serum neutralizationSerum NeutralizationVaccineVeterinary vaccineZoetis

Identifiers

PMID35339817
PMCPMC8915440
OpenAlexW4220684769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.