Evidence map›Paper›PMID 35339639›Full record

ArticleJournal of clinical epidemiology2022

An evaluation of the COVID-19 recommendation map identified diverging clinical and public health guidance.

Zil H Nasir, Dominik Mertz, Robby Nieuwlaat, Nancy Santesso, Tamara Lotfi, Ashley Motilall, Lorenzo Moja, Lawrence Mbuagbaw, Miloslav Klugar, Alexis F Turgeon and 22 more

Abstract read
In one paragraph

Article in Journal of clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Zil H NasirDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada.
Dominik MertzDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Robby NieuwlaatDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Nancy SantessoDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada.
Tamara LotfiDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada.
Ashley MotilallDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada.
Lorenzo MojaDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Lawrence MbuagbawDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Biostatistics Unit/The Research Institute, St Joseph's Healthcare, Hamilton, Ontario, Canada.
Miloslav KlugarCzech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic; Institute of Health Information and Statistics of the Czech Republic, Palackého náměstí 4, 128 01 Prague 2, Czech Republic.
Alexis F TurgeonDepartment of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, Québec City, Canada; Population Health and Optimal Health Practices Research Unit, CHU de Québec - Université Laval Research Center, Québec City, Canada.
Joseph L MathewPostgraduate Institute of Medical Education and Research, Chandigarh, India.
Carlos Canelo-AybarIberoamerican Cochrane Centre Department of Clinical Epidemiology and Public Health, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
Kevin PottieBruyere Research Institute, Centre for Studies in Family Medicine, Western University, London Ontario N6A 3K7, Canada.
Omar DewidarSchool of Epidemiology and Public Health, University of Ottawa, Canada; Bruyere Research Institute, Ottawa, Canada.
Miranda W LangendamAmsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands.
Alfonso IorioDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Gunn Elisabeth VistNorwegian Institute of Public Health, P. O. Box 222 Skøyen, 0213 Oslo, Norway.
Joerg J MeerpohlInstitute for Evidence in Medicine, Medical Center & Faculty of Medicine, University of Freiburg, Freiburg, Germany; Cochrane Germany, Cochrane Germany Foundation, Freiburg, Germany.
Signe FlottorpNorwegian Institute of Public Health, P. O. Box 222 Skøyen, 0213 Oslo, Norway; University of Oslo, P.O. Box 1130, Blindern 0318, Oslo, Norway.
Tamara KredoCochrane South Africa, South African Medical Research Council, Cape Town, South Africa; Division of Clinical Pharmacology, Department of Medicine, and Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University, Cape Town, South Africa.
Thomas PiggottDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada.
Micayla MathewsDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada.
Amir QaseemAmerican College of Physicians, Philadelphia, PA, USA.
Derek K ChuDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Peter TugwellSchool of Epidemiology and Public Health, University of Ottawa, Canada; Bruyere Research Institute, Ottawa, Canada; Department of Medicine, University of Ottawa, Ottawa Ontario K1H 8M5, Canada.
Jitka KlugarováCzech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic; Institute of Health Information and Statistics of the Czech Republic, Palackého náměstí 4, 128 01 Prague 2, Czech Republic.
Harrison NelsonFaculty of Health Sciences, Queen's University, 18 Barrie Street, Kingston, Ontario K7L 3N6, Canada.
Heba HusseinFaculty of Dentistry, Department of Oral Medicine and Periodontology, Cairo University, Cairo, Egypt.
Jozef SuvadaDepartments of Science and International Studies, St. Elizabeth University of Public Health and Social Science, Bratislava, Slovak Republic.
Ignacio NeumannDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Internal Medicine, Pontificia Universidad Catolica de Chile, Avenida Libertador General Bernardo O'Higgins 340, Santiago, Chile.
Holger J SchünemannDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Michael G. DeGroote Cochrane Canada and GRADE Centre, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Cochrane Germany, Cochrane Germany Foundation, Freiburg, Germany; Dipartimento di Scienze Biomediche Humanitas University, Milan, Italy. Electronic address: schuneh@mcmaster.ca.
eCOVID-19 recommendations map Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe divergence between actionable statements issued by coronavirus disease 2019 (COVID-19) guideline developers cataloged on the "COVID-19 Recommendations and Gateway to Contextualization" platform. STUDY DESIGN AND

settingWe defined divergence as at least two comparable actionable statements with different explicit judgments of strength, direction, or subgroup consideration of the population or intervention. We applied a content analysis to compare guideline development methods for a sample of diverging statements and to evaluate factors associated with divergence.

resultsOf the 138 guidelines evaluated, 85 (62%) contained at least one statement that diverged from another guideline. We identified 223 diverging statements in these 85 guidelines. We grouped statements into 66 clusters. Each cluster addressed the same population, intervention, and comparator group or just similar interventions. Clinical practice statements were more likely to diverge in an explicit judgment of strength or direction compared to public health statements. Statements were more likely to diverge in strength than direction. The date of publication, used evidence, interpretation of evidence, and contextualization considerations were associated with divergence.

conclusionMore than half of the assessed guidelines issued at least one diverging statement. This study helps in understanding the types of differences between guidelines issuing comparable statements and factors associated with their divergence.

Indexed as

COVID-19Public HealthHumansCOVID-19DiscordanceDivergenceGRADEGuidelinesRecommendations

Identifiers

PMID35339639
PMCPMC8942881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.