Evidence map›Paper›PMID 35339491›Full record

ArticleThe Journal of biological chemistry2022

Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.

Yue Ren, Yang Li, Yaojie Wang, Tianlei Wen, Xuhang Lu, Shenghai Chang, Xing Zhang, Yuequan Shen, Xue Yang

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. CALHM5 deficiency alleviates aortic aneurysm by regulating smooth muscle calcium homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. A mechanism of CALHM1 ion channel gating.American journal of physiology. Cell physiology · 2025
    Article
  5. PANX1 hexamers work but cells prefer heptamers.The Journal of general physiology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yue RenState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yang LiState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Yaojie WangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Tianlei WenState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Xuhang LuState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
Shenghai ChangDepartment of Biophysics, Zhejiang University School of Medicine, Hangzhou, China; Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Center of Cryo Electron Microscopy, Zhejiang University School of Medicine, Hangzhou, China.
Xing ZhangDepartment of Biophysics, Zhejiang University School of Medicine, Hangzhou, China; Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Center of Cryo Electron Microscopy, Zhejiang University School of Medicine, Hangzhou, China.
Yuequan ShenState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China; Synergetic Innovation Center of Chemical Science and Engineering, Tianjin, China. Electronic address: yshen@nankai.edu.cn.
Xue YangState Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China. Electronic address: yangxue@nankai.edu.cn.
Nankai University · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium homeostasis modulator 1 (CALHM1) is a voltage- and Ca

Indexed as

Adenosine TriphosphateCalcium ChannelsZebrafish ProteinsAnimalsCalciumCryoelectron MicroscopyHomeostasisZebrafishAdenosine TriphosphateCalciumCalcium ChannelsZebrafish ProteinsassemblyATP permeationcalcium homeostasis modulatorCALHM1cryo-EMgating mechanism

Identifiers

PMID35339491
PMCPMC9035704
OpenAlexW4221029889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.