ArticleThe Veterinary record2022
Increasing resistance to multiple anthelmintic classes in gastrointestinal nematodes on sheep farms in southwest England.
Article in The Veterinary record, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- FEC Check: Development of a decision support tool to aid interpretation of gastrointestinal nematode faecal egg counts in sheep.The Veterinary record · 2026Article
- Integrated epidemiology and multi-assay evidence of anthelmintic resistance in ovine gastrointestinal nematodes of Northern India.Scientific reports · 2026Article
- Aptazyme-mediated gene regulation in Strongyloides stercoralis for functional studies of insulin receptor isoform specificity.PLoS pathogens · 2025Article
- Evaluation of lyophilizedVeterinary world · 2025Article
- Use of a Novel Real-Time PCR to Investigate Anthelmintic Efficacy AgainstVeterinary sciences · 2025Article
- Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta.PLoS pathogens · 2025Article
- Study on the effect of GCY-12 gene on albendazole sensitivity ofFrontiers in veterinary science · 2025Article
- Investigation on parasite infection and anthelmintic resistance of gastrointestinal nematodes in sheep in Hinggan league (City), China.BMC veterinary research · 2024Article
- Phytochemicals, antioxidant ability and in vitro anthelmintic activity of crude extracts fromJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- Synergistic Interaction Effect of Artemisia cina n-hexane Extract and Tagetes lucida Ethyl Acetate Extract on Haemonchus Contortus.Acta parasitologica · 2024Article
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- Increasing resistance to multiple anthelmintic classes in gastrointestinal nematodes on sheep farms in southwest England.The Veterinary record · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAnthelmintic resistance (AR) in gastrointestinal nematodes (GIN) is increasing globally, and farmers are encouraged to adopt sustainable control measures. Haemonchus contortus is increasingly reported in the UK, potentially complicating effective GIN control.
methodsFaecal egg count reduction tests (FECRT) were conducted on 13 farms in north Devon, England, UK in 2016. Relative abundance of H. contortus was quantified using peanut agglutinin staining and used to estimate faecal egg count reduction percentages (FECR%) using the eggCounts R package.
resultsOn average, farms had GIN resistance to three anthelmintic classes. No farms had susceptibility to all anthelmintics tested. AR was more prevalent in 2016 than on the same farms in 2013. H. contortus was present on 85% of the farms tested and comprised on average 6% (0%-52%) of GIN eggs before treatment. Resistance or suspected resistance to all anthelmintics tested was observed in this species on different farms.
conclusionThe results demonstrate diversity of AR profiles on farms, apparent progression of AR within a 3-year period, and challenges detecting AR in mixed-species infections. Where possible, interpretation of mixed-species FECRT should take into account the relative abundance of species pre- and post-treatment to identify pragmatic treatment options targeting individual genera.
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