ArticlePharmacology research & perspectives2022
The effects of apixaban on clot characteristics in atrial fibrillation: A novel pharmacodynamic biomarker.
Article in Pharmacology research & perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The impact of physical activity and intensity on clot mechanical microstructure and contraction in middle-aged/older habitual runners.BMC neurology · 2025Article
- Edoxaban Overdose in a Child: Unexpected Observation of Clot Lysis.TH open : companion journal to thrombosis and haemostasis · 2025Article
- CHAAnnals of clinical and translational neurology · 2024Article
- The effects of apixaban on clot characteristics in atrial fibrillation: A novel pharmacodynamic biomarker.Pharmacology research & perspectives · 2022Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atrial fibrillation (AF) is a major risk factor for stroke. We aim to characterize AF patients and the effects of apixaban therapy in terms of clot microstructure using gel point analysis, a novel biomarker. Seventy-eight patients were included in the study, 50 Stroke with AF (AF-S), and 28 AF without stroke (AF). Pre- and post-anticoagulation samples were collected: gel point (GP) analysis was performed to obtain (i) TGP (the time taken to reach the GP or the clot formation time) and (ii) d
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