Evidence map›Paper›PMID 35338534›Full record

Trial reportJournal of traumatic stress2022

Treating posttraumatic stress disorder at home in a single week using 1-week virtual massed cognitive processing therapy.

Philip Held, Merdijana Kovacevic, Kelsey Petrey, Enya A Meade, Sarah Pridgen, Mauricio Montes, Brianna Werner, Michelle L Miller, Dale L Smith, Debra Kaysen and 1 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of traumatic stress, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06429293 (Impact of Cognitive Behavioral Therapy on Neural, Inflammatory, & Autonomic Markers in a Sample With PTSD and Cardiovascular Risk), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06429293 narecruitingnot on this mapstarted 2023, after this paper: background citation

Impact of Cognitive Behavioral Therapy on Neural, Inflammatory, & Autonomic Markers in a Sample With PTSD and Cardiovascular Risk: Protocol for a Pilot Randomized Controlled Trial

TypeinterventionalSponsorMassachusetts General HospitalRan2023 to 2026Enrolled30ConditionsPosttraumatic Stress DisorderArmsCognitive processing therapy
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Examining treatment outcomes for military service members in an intensive treatment program for posttraumatic stress disorder.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2026
    Article
  7. Article
  8. Article
  9. Widening the scope of intensive treatment for PTSD in the military health system.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2024
    Article
  10. Clinical Education: Addressing Prior Trauma and Its Impacts in Medical Settings.Journal of clinical psychology in medical settings · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Support for Policy Changes for Therapy Related to Homefront Missions.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Philip HeldDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0003-3974-1802
Merdijana KovacevicDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0001-8906-7698
Kelsey PetreyDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0002-1422-5898
Enya A MeadeDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0002-3721-3398
Sarah PridgenDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0002-2640-8050
Mauricio MontesDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0002-3497-1986
Brianna WernerDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0003-1857-3256
Michelle L MillerDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0001-6150-0242
Dale L SmithDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0003-0854-9973
Debra KaysenDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-7961-2787
Niranjan S KarnikDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Illinois, USA.ORCID 0000-0001-7650-3008
Rush University Medical Center · USIndiana University School of MedicineOlivet Nazarene University · USVA Palo Alto Health Care System · US

Funding

Institutional Career Development Core (Chapter 1)KL2TR002387 · NCATS · UNIVERSITY OF CHICAGO · PI ERIC C BEYER, Lisa L Barnes · 2017 to 2026
$7.6M
NCATS NIH HHS KL2 TR002387
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) treatments are increasingly delivered in massed formats and have shown comparable results to standard, weekly treatment. To date, massed cognitive processing therapy (CPT), delivered daily, has been delivered primarily in combination with adjunctive services and among veteran populations, but it has not been rigorously evaluated as a standalone intervention. The present study evaluated 1-week massed CPT delivered virtually (i.e., via telehealth) to a community sample of trauma-exposed individuals (N = 24). Using a single-arm open-label design, participants received CPT twice per day for 5 days. The results indicated that most participants completed treatment (n = 23, 95.8%), and no adverse events were reported. Participants exhibited large reductions in clinician-rated, d = 2.01, and self-reported PTSD symptoms, d = 2.55, as well as self-reported depressive symptoms, d = 1.46. On average, participants reported a 5-point PTSD symptom reduction and 1-point reduction in depressive symptoms for each treatment day. Reductions in PTSD and depressive symptoms were maintained at 3-month follow-up. Overall, 1-week massed CPT delivered virtually was shown to be feasible and to result in rapid symptom reductions that were sustained over time. Virtual massed CPT has the potential to increase access to effective treatments and help trauma survivors restore aspects of their lives in short amounts of time.

Indexed as

Cognitive Behavioral TherapyStress Disorders, Post-TraumaticVeteransHumansMental ProcessesTreatment Outcome

Identifiers

PMID35338534
PMCPMC9357038
OpenAlexW4220989975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.