Evidence map›Paper›PMID 35338435›Full record

ArticleNeurocritical care2022

Risk Factors for Mechanical Ventilation in Patients with Guillain-Barré Syndrome.

Yanwei Cheng, Kangding Liu, Chunrong Li, Weiwei Zhang, Xiujuan Wu, Shaokuan Fang

Abstract read
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yanwei ChengDepartment of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, China.
Kangding LiuDepartment of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, China.
Chunrong LiDepartment of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, China.
Weiwei ZhangDepartment of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, China.
Xiujuan WuDepartment of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, China. wuxiujuan861003@jlu.edu.cn.
Shaokuan FangDepartment of Neurology, Neuroscience Center, The First Hospital of Jilin University, Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, China. fangsk@jlu.edu.cn.ORCID http://orcid.org/0000-0002-7980-281X
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory support is required in 20-30% of patients with Guillain-Barré syndrome (GBS). We investigated clinical and biological risk factors for mechanical ventilation (MV) in northeast China through a retrospective GBS study. The Erasmus GBS Respiratory Insufficiency Score (EGRIS) is a prognostic model for MV in patients with GBS, and its usefulness has been validated in several countries but not in China. Therefore, we intended to validate the EGRIS model in our GBS cohort.

methodsA total of 252 patients with GBS were included in this study from January 2013 to October 2017. Risk factors for MV were identified via multivariate logistic regression analysis. The prognostic value of the EGRIS was validated via receiver operating characteristic curve analysis.

resultsThirty-one patients (12.3%) required MV (mean age 54.19 years), with a majority being male (77.4%). The risk factors for MV were male sex [odds ratio (OR) 3.720, 95% confidence interval (CI) 1.155-11.985, p < 0.05], shorter interval from onset to admission (OR 0.830, 95% CI 0.711-0.970, p < 0.05), lower Medical Research Council sum score at admission (OR 0.942, 95% CI 0.911-0.973, p < 0.001), neutrophil-to-lymphocyte ratio at admission (OR 1.174, 95% CI 1.049-1.315, p < 0.01), and cranial nerve deficit (OR 3.805, 95% CI 1.373-10.541, p < 0.05). The EGRIS had a good predictive ability for MV (area under the receiver operating curve 0.861) in patients with GBS, and a high EGRIS was a predictor for MV (OR 8.778, 95% CI 3.432-22.448, p < 0.001). However, there was no significant difference in ganglioside administration between ventilated and nonventilated patients.

conclusionsAn elevated neutrophil-to-lymphocyte ratio at admission and a high EGRIS could serve as predictors for MV in our GBS cohort.

Indexed as

Guillain-Barre SyndromeRespiratory InsufficiencyFemaleHumansMaleMiddle AgedRespiration, ArtificialRetrospective StudiesRisk FactorsErasmus GBS Respiratory Insufficiency ScoreGangliosideGuillain–Barré syndrome (GBS)Mechanical ventilationNeutrophil-to-lymphocyte ratio

Identifiers

PMID35338435
OpenAlexW4220655629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.