Evidence map›Paper›PMID 35338254›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2022

Hormonal milieu drives economic demand for cocaine in female rats.

Amy S Kohtz, Belle Lin, Hannah Davies, Mark Presker, Gary Aston-Jones

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amy S KohtzBrain Health Institute, Rutgers University, Piscataway, NJ, 08854, USA. akohtz@umc.edu.
Belle LinBrain Health Institute, Rutgers University, Piscataway, NJ, 08854, USA.
Hannah DaviesBrain Health Institute, Rutgers University, Piscataway, NJ, 08854, USA.ORCID http://orcid.org/0000-0002-8460-5159
Mark PreskerBrain Health Institute, Rutgers University, Piscataway, NJ, 08854, USA.
Gary Aston-JonesBrain Health Institute, Rutgers University, Piscataway, NJ, 08854, USA. gsa35@ca.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
ROLE OF OREXIN IN COCAINE DEMAND AND ADDICTIONR01DA006214 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI ASTON-JONES, GARY S. · 1989 to 2024
$6.0M
Role of Extended Amygdala in Opiate and Cocaine AbuseR37DA006214 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI ASTON-JONES, GARY S. · 2003 to 2012
$4.2M
Sex Differences in AddictionR00DA045758 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI KOHTZ, AMY · 2022 to 2024
$747k
Sex Differences in AddictionK99DA045758 · NIDA · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI KOHTZ, AMY · 2019 to 2020
$301k
NIDA NIH HHS K99 DA045758NIDA NIH HHS R00 DA045758NIDA NIH HHS R01 DA006214NIDA NIH HHS R37 DA006214NIEHS NIH HHS T32 ES007148
6 · The paper itself

Abstract

There are substantial sex differences in drug abuse, and a key feature of cocaine addiction is pathologically high motivation for drug. We investigated the role of ovarian hormones on cocaine demand in female rats using a within-session threshold behavioral economics (BE) procedure, which allows us to compare motivation for drug across hormonal states and sex while controlling for differences in dose and intake. This approach quantifies demand elasticity (α) and free consumption (Q

Indexed as

CocaineCocaine-Related DisordersAnimalsEconomics, BehavioralFemaleMaleRatsRats, Sprague-DawleySelf AdministrationCocaine

Identifiers

PMID35338254
PMCPMC9205886
OpenAlexW4220930685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.