Evidence map›Paper›PMID 35338132›Full record

ArticleNature communications2022

Aegilops sharonensis genome-assisted identification of stem rust resistance gene Sr62.

Guotai Yu, Oadi Matny, Nicolas Champouret, Burkhard Steuernagel, Matthew J Moscou, Inmaculada Hernández-Pinzón, Phon Green, Sadiye Hayta, Mark Smedley, Wendy Harwood and 30 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
22.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
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  5. Review
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  7. Review
  8. Article
  9. Review
  10. Introgression of stem rust resistance gene Sr68 from Thinopyrum junceum into wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  11. Article
  12. Article
  13. Identification of a novel QTL associated with Fusarium head blight resistance on chromosome 3B in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  14. Article
  15. Article
  16. Progress and innovations of gene cloning in wheat and its close relatives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Sequencing Trait-Associated Mutations (STAM) to Clone Rust Resistance Genes.Methods in molecular biology (Clifton, N.J.) · 2025
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 12 institutions in 10 countries.

Guotai YuJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
Oadi MatnyDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, 55108, USA.ORCID 0000-0002-8447-2886
Nicolas ChampouretThe Sainsbury Laboratory, University of East Anglia, Norwich, NR4 7UK, UK.
Burkhard SteuernagelJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.ORCID 0000-0002-8284-7728
Matthew J MoscouThe Sainsbury Laboratory, University of East Anglia, Norwich, NR4 7UK, UK.ORCID 0000-0003-2098-6818
Inmaculada Hernández-PinzónThe Sainsbury Laboratory, University of East Anglia, Norwich, NR4 7UK, UK.ORCID 0000-0003-3711-2893
Phon GreenThe Sainsbury Laboratory, University of East Anglia, Norwich, NR4 7UK, UK.ORCID 0000-0002-1968-0574
Sadiye HaytaJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.ORCID 0000-0003-2920-4720
Mark SmedleyJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.ORCID 0000-0002-6162-4795
Wendy HarwoodJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.ORCID 0000-0002-4323-9009
Ngonidzashe KangaraJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
Yajuan YueJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
Catherine GardenerJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.
Mark J BanfieldJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.ORCID 0000-0001-8921-3835
Pablo D OliveraDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, 55108, USA.
Cole WelchinDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, 55108, USA.
Jamie SimmonsDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, 55108, USA.
Eitan MilletInstitute for Cereal Crops Improvement, Tel Aviv University, Tel Aviv, Israel.
Anna Minz-DubInstitute for Cereal Crops Improvement, Tel Aviv University, Tel Aviv, Israel.
Moshe RonenInstitute for Cereal Crops Improvement, Tel Aviv University, Tel Aviv, Israel.
Raz AvniInstitute for Cereal Crops Improvement, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-0801-5093
Amir SharonSchool of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-6045-9169
Mehran PatpourDepartment of Agroecology, Aarhus University, Forsøgsvej 1, DK-4200, Slagelse, Denmark.ORCID 0000-0002-4914-2697
Annemarie F JustesenDepartment of Agroecology, Aarhus University, Forsøgsvej 1, DK-4200, Slagelse, Denmark.
Murukarthick JayakodiLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID 0000-0003-2951-0541
Axel HimmelbachLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.
Nils SteinLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID 0000-0003-3011-8731
Shuangye WuDepartment of Agronomy, Kansas State University, Manhattan, KS, 66506, USA.
Jesse PolandDepartment of Agronomy, Kansas State University, Manhattan, KS, 66506, USA.ORCID 0000-0002-7856-1399
Jennifer EnsCrop Development Centre, Department of Plant Sciences, University of Saskatchewan, Saskatoon, SK, Canada.ORCID 0000-0003-2663-1006
Curtis PozniakCrop Development Centre, Department of Plant Sciences, University of Saskatchewan, Saskatoon, SK, Canada.ORCID 0000-0002-7536-3856
Miroslava KarafiátováInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, 779 00, Olomouc, Czech Republic.ORCID 0000-0003-1177-6472
István MolnárInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, 779 00, Olomouc, Czech Republic.
Jaroslav DoleželInstitute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, 779 00, Olomouc, Czech Republic.ORCID 0000-0002-6263-0492
Eric R WardThe Sainsbury Laboratory, University of East Anglia, Norwich, NR4 7UK, UK.ORCID 0000-0001-6959-6189
T Lynne Reuber2Blades Foundation, Evanston, IL, USA.
Jonathan D G JonesThe Sainsbury Laboratory, University of East Anglia, Norwich, NR4 7UK, UK.ORCID 0000-0002-4953-261X
Martin MascherLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany.ORCID 0000-0001-6373-6013
Brian J SteffensonDepartment of Plant Pathology, University of Minnesota, St. Paul, MN, 55108, USA. bsteffen@umn.edu.ORCID 0000-0001-7961-5363
Brande B H WulffJohn Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK. brande.wulff@kaust.edu.sa.ORCID 0000-0003-4044-4346
John Innes Centre · GBUniversity of East Anglia · GBTel Aviv University · ILUniversity of Minnesota · USLeibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) · DEAarhus University · DKCzech Academy of Sciences, Institute of Experimental Botany · CZKansas State University · USUniversity of Saskatchewan · CACentre for Agricultural Research · HUGerman Centre for Integrative Biodiversity Research · DEMystic Seaport · US

Funding

Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9780
6 · The paper itself

Abstract

The wild relatives and progenitors of wheat have been widely used as sources of disease resistance (R) genes. Molecular identification and characterization of these R genes facilitates their manipulation and tracking in breeding programmes. Here, we develop a reference-quality genome assembly of the wild diploid wheat relative Aegilops sharonensis and use positional mapping, mutagenesis, RNA-Seq and transgenesis to identify the stem rust resistance gene Sr62, which has also been transferred to common wheat. This gene encodes a tandem kinase, homologues of which exist across multiple taxa in the plant kingdom. Stable Sr62 transgenic wheat lines show high levels of resistance against diverse isolates of the stem rust pathogen, highlighting the utility of Sr62 for deployment as part of a polygenic stack to maximize the durability of stem rust resistance.

Indexed as

AegilopsBasidiomycotaDisease ResistanceGenes, PlantPlant BreedingPlant DiseasesTriticum

Identifiers

PMID35338132
PMCPMC8956640
OpenAlexW4220874070

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.