Evidence map›Paper›PMID 35338096›Full record

ReviewRespiratory care2022

Intravascular Gas Exchange: Physiology, Literature Review, and Current Efforts.

Tobias L Straube, Stewart Farling, Marc A Deshusses, Bruce Klitzman, Ira M Cheifetz, Travis P Vesel

Open access · greenAbstract readReview
In one paragraph

Review in Respiratory care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tobias L StraubeDepartment of Pediatrics, Duke University School of Medicine, Durham, North Carolina. tobias.straube@duke.edu.
Stewart FarlingDepartment of Civil and Environmental Engineering, Duke University, Durham, North Carolina.
Marc A DeshussesDepartment of Civil and Environmental Engineering, Duke University, Durham, North Carolina; and Duke Global Health Institute, Duke University, Durham, North Carolina.
Bruce KlitzmanKenan Plastic Surgery Research Labs, Duke University School of Medicine, Durham, North Carolina; and Department of Biomedical Engineering, Duke University, Durham, North Carolina.
Ira M CheifetzDepartment of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Travis P VeselDepartment of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Duke University · USRainbow Babies & Children's Hospital · US

Funding

Unified Program for Therapeutics in Children (UPTiC)T32HD094671 · NICHD · DUKE UNIVERSITY · PI Ian J Davis, Kanecia Obie Zimmerman · 2019 to 2026
$2.9M
NICHD NIH HHS T32 HD094671
6 · The paper itself

Abstract

Acute respiratory failure with inadequate oxygenation and/or ventilation is a common reason for ICU admission in children and adults. Despite the morbidity and mortality associated with acute respiratory failure, few proven treatment options exist beyond invasive ventilation. Attempts to develop intravascular respiratory assist catheters capable of providing clinically important gas exchange have had limited success. Only one device, the IVOX catheter, was tested in human clinical trials before development was halted without FDA approval. Overcoming the technical challenges associated with providing safe and effective gas exchange within the confines of the intravascular space remains a daunting task for physicians and engineers. It requires a detailed understanding of the fundamentals of gas transport and respiratory physiology to optimize the design for a successful device. This article reviews the potential benefits of such respiratory assist catheters, considerations for device design, previous attempts at intravascular gas exchange, and the motivation for continued development efforts.

Indexed as

Respiratory Distress SyndromeRespiratory InsufficiencyAdultCarbon DioxideChildHumansPulmonary Gas ExchangeRespirationCarbon DioxideARDShypoxemiaintravascular gas exchangeintravascular oxygenatormembrane oxygenationrespiratory assist catheterrespiratory failure

Identifiers

PMID35338096
PMCPMC9994006
OpenAlexW4220810261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.