Evidence map›Paper›PMID 35337309›Full record

ArticleBMC complementary medicine and therapies2022

In vitro antibacterial and cytotoxic effects of Euphorbia grandicornis Blanc chemical constituents.

Douglas Kemboi, Moses K Langat, Xavier Siwe-Noundou, Rui W M Krause, Michelle Louise Isaacs, Vuyelwa Jacqueline Tembu

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Article in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Green Synthesis of Silver Nanoparticles UsingMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Douglas KemboiDepartment of Chemistry, Tshwane University of Technology, Pretoria, 0001, South Africa. kemboidouglas01@gmail.com.
Moses K LangatRoyal Botanic Gardens Kew, Kew Green, Richmond, Surrey, TW9 3AE, UK.
Xavier Siwe-NoundouPharmaceutical Sciences Department, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, 0204, South Africa.
Rui W M KrauseDepartment of Chemistry, Rhodes University, Makhanda (Grahamstown), 6140, South Africa.
Michelle Louise IsaacsDepartment of Biochemistry and Microbiology, Rhodes University, Makhanda (Grahamstown),, 6140, South Africa.
Vuyelwa Jacqueline TembuDepartment of Chemistry, Tshwane University of Technology, Pretoria, 0001, South Africa. TembuVJ@tut.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEuphorbia grandicornis is widely utilized in traditional medicine for the treatment of microbial infections including sexually transmitted diseases such as syphilis, gonorrhoea and for healing of wounds.

objectiveThe aim of this work was to isolate and evaluate the antibacterial and anticancer activities of Euphorbia grandicornis chemical constituents.

methodsChemical constituents were isolated and identified using various spectroscopic techniques such as IR, MS, and NMR. The single point growth inhibitory potential of the compounds was determined using a 96-well plate based assay.

resultsThe CH

conclusionThe results obtained from this study indicate that E. grandicornis, is a rich source of chemical constituents that may provide new lead compounds for the development of antibacterial agents.

Indexed as

EuphorbiaAnti-Bacterial AgentsChromatography, LiquidEscherichia coliHeLa CellsHumansMicrobial Sensitivity TestsPlant ExtractsStaphylococcus aureusTandem Mass SpectrometryAnti-Bacterial AgentsPlant ExtractsChemical constituentsEuphorbia grandicornisStaphylococcus aureus ATCC 6538 and Escherichia coli ATCC 8739

Identifiers

PMID35337309
PMCPMC8957186

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