Evidence map›Paper›PMID 35337276›Full record

ArticleBMC geriatrics2022

Prospective telehealth analysis of functional performance, frailty, quality of life, and mental health after COVID-19 hospitalization.

Jacob J Capin, Melissa P Wilson, Kristine Hare, Swati Vempati, Carley E Little, Donna McGregor, Jose Castillo-Mancilla, Jennifer E Stevens-Lapsley, Sarah E Jolley, Kristine M Erlandson

Abstract read
In one paragraph

Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacob J CapinPhysical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Melissa P WilsonDepartment of Bioinformatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Kristine HarePhysical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Swati VempatiDivision of Infectious Diseases, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave, Mail Stop B168, Aurora, CO, 80045, USA.
Carley E LittleSchool of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Donna McGregorDivision of Infectious Diseases, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave, Mail Stop B168, Aurora, CO, 80045, USA.
Jose Castillo-MancillaDivision of Infectious Diseases, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave, Mail Stop B168, Aurora, CO, 80045, USA.
Jennifer E Stevens-LapsleyPhysical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Sarah E JolleyDivision of Pulmonary and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Kristine M ErlandsonDivision of Infectious Diseases, University of Colorado Anschutz Medical Campus, 12700 E. 19th Ave, Mail Stop B168, Aurora, CO, 80045, USA. Kristine.erlandson@cuanschutz.edu.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID SurvivorsR01AG054366 · NIA · UNIVERSITY OF COLORADO DENVER · PI ERLANDSON, KRISTINE MACE, STEVENS-LAPSLEY, JENNIFER E. · 2016 to 2020
$3.4M
Prevalence of ICU-Acquired Myopathy in Patients with Alcohol Use DisordersK23AA026315 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI JOLLEY, SARAH E · 2018 to 2022
$696k
Contralateral Knee Osteoarthritis Among Older Adults after Primary Total Knee ArthroplastyF32AG066274 · NIA · UNIVERSITY OF COLORADO DENVER · PI CAPIN, JACOB J · 2019 to 2021
$94k
NCATS NIH HHS UL1 TR002535NIAAA NIH HHS K23 AA026315NIA NIH HHS F32 AG066274NIA NIH HHS R01 AG054366
6 · The paper itself

Abstract

backgroundCOVID-19 is a global pandemic with poorly understood long-term consequences. Determining the trajectory of recovery following COVID-19 hospitalization is critical for prioritizing care, allocating resources, facilitating prognosis, and informing rehabilitation. The purpose of this study was to prospectively evaluate recovery following COVID-19 hospitalization.

methodsParticipants age 18 years or older who were hospitalized for ≥24 h due to COVID-19 completed phone/video call virtual assessments (including the 10-time chair rise test) and survey forms at three time points (2-6, 12, and 18 weeks) after hospital discharge. Univariate logistic and linear regression models assessed the associations of the outcomes with primary predictors (categorical age, sex, race/ethnicity group, and categorical pre-hospitalization frailty) at baseline; the same were used to assess differences in change from week 2-6 (continuous outcomes) or outcome persistence/worsening (categorical) at last contact.

resultsOne hundred nine adults (age 53.0 [standard deviation 13.1]; 53% female) participated including 43 (39%) age 60 or greater; 59% identified as an ethnic and/or racial minority. Over 18 weeks, the mean time to complete the 10-time chair rise test decreased (i.e., improved) by 6.0 s (95% CI: 4.1, 7.9 s; p < 0.001); this change did not differ by pre-hospital frailty, race/ethnicity group, or sex, but those age ≥ 60 had greater improvement. At weeks 2-6, 67% of participants reported a worse Clinical Frailty Scale category compared to their pre-hospitalization level, whereas 42% reported a worse frailty score at 18 weeks. Participants who did not return to pre-hospitalization levels were more likely to be female, younger, and report a pre-hospitalization category of 'very fit' or 'well'.

conclusionsWe found that functional performance improved from weeks 2-6 to 18 weeks of follow-up; that incident clinical frailty developed in some individuals following COVID-19; and that age, sex, race/ethnicity, and pre-hospitalization frailty status may impact recovery from COVID-19. Notably, individuals age 60 and older were more likely than those under age 45 years to return to their pre-hospitalization status and to make greater improvements in functional performance. The results of the present study provide insight into the trajectory of recovery among a representative cohort of individuals hospitalized due to COVID-19.

Indexed as

COVID-19FrailtyTelemedicineFemaleHospitalizationHumansMaleMental HealthPhysical Functional PerformanceProspective StudiesQuality of LifeCOVID19FrailtyFunctionPosttraumatic stress disorderQuality of lifeRecovery

Identifiers

PMID35337276
PMCPMC8956362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.