Evidence map›Paper›PMID 35337046›Full record

ArticleViruses2022

Characterisation of Particle Size and Viability of SARS-CoV-2 Aerosols from a Range of Nebuliser Types Using a Novel Sampling Technique.

Susan Paton, Simon Clark, Antony Spencer, Isobel Garratt, Ikshitaa Dinesh, Katy-Anne Thompson, Allan Bennett, Thomas Pottage

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Concentrating viable airborne pathogens using a virtual impactor with a compact water-based condensation air sampler.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2024
    Article
  6. Article
  7. Article
  8. Room-Based Assessment of Mobile Air Cleaning Devices Using a Bioaerosol Challenge.Applied biosafety : journal of the American Biological Safety Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Susan PatonUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.ORCID 0000-0002-0744-9412
Simon ClarkUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.
Antony SpencerUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.
Isobel GarrattUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.ORCID 0000-0001-9682-4757
Ikshitaa DineshUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.
Katy-Anne ThompsonUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.
Allan BennettUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.
Thomas PottageUK Health Security Agency (UKHSA), Porton Down, Salisbury SP4 0JG, UK.
UK Health Security Agency · GB

Funding

Medical Research Council COV220-143 COVID-19Medical Research Council MC_PC_19064
6 · The paper itself

Abstract

Little is understood about the impact of nebulisation on the viability of SARS-CoV-2. In this study, a range of nebulisers with differing methods of aerosol generation were evaluated to determine SARS-CoV-2 viability following aerosolization. The aerosol particle size distribution was assessed using an aerosol particle sizer (APS) and SARS-CoV-2 viability was determined after collection into liquid media using All-Glass Impingers (AGI). Viable particles of SARS-CoV-2 were further characterised using the Collison 6-jet nebuliser in conjunction with novel sample techniques in an Andersen size-fractioning sampler to predict lung deposition profiles. Results demonstrate that all the tested nebulisers can generate stable, polydisperse aerosols (Geometric standard deviation (GSD) circa 1.8) in the respirable range (1.2 to 2.2 µm). Viable fractions (VF, units PFU/particle, the virus viability as a function of total particles produced) were circa 5 × 10

Indexed as

COVID-19SARS-CoV-2AerosolsAnimalsNebulizers and VaporizersParticle SizeAerosolsaerosolsparticlesrespirablesamplingSARS-CoV-2sizingviable

Identifiers

PMID35337046
PMCPMC8950415
OpenAlexW4221023189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.